Institut de Chimie Moléculaire et des Matériaux d'Orsay

Méthodologie, Synthèse et Molécules Thérapeutiques

Modern Methods for Natural Product Synthesis

Methodological and Synthetic Developments of Heterocycloaddition Reactions

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We are currently studying the méthodological and synthetic aspects of cycloaddition reactions, especially the nitroso Diels-Alder reaction:selectivities, new reactions, synthetic applications.

Project Manager: Cyrille Kouklovsky

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Amino Acid and Peptide Chemistry

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We develop new original concepts for the selective synthesis of new amino acids: β,γ-diamino acids, quaternary aminoacid, and incorporate them into peptide structures.

Project Manager: Valérie Alezra

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Indole Chemistry and Total Synthesis

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We study the chemistry of the indole nucleus. We aim to develop original strategies towards dearomatizations of indoles in order to obtain biologically relevant three dimensional scaffolds and to achieve the total synthesis of indoline-containing natural products.

Project Manager: Guillaume Vincent

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Synthesis and Reactivities of Unsaturated Aminophophonates

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Our research focuses on the highly selective synthesis of aminophosphonate synthons and there use in the preparation of more complex molecules such as spirodienone lactams.

Project Manager: Nicolas Rabasso

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