Institut de Chimie Moléculaire et des Matériaux d'Orsay

Giang Vo thanh

Bât. 670, bureau 2304 – LCM – ICMMO - UMR 8182
Université Paris-Saclay
Bâtiment 670
17-19 Avenue des Sciences
91400 Orsay

+33 1 69 15 78 91

Giang Vo-Thanh obtained his Ms in 1994 and his Ph.D in 1997 from the University ‘Pierre et Marie Curie’ (Paris VI). After three year postdoctoral fellowships, he took up, in 2001, an academic position as an assistant professor at the University Paris-Sud. In 2006, he obtained his Habilitation diploma and in 2007, he was pointed Full Professor at the University Paris-Sud. His research interests include all aspects of synthetic methodology, including the design and synthesis of chiral ionic liquids and their uses as chiral reaction media (solvent and/or catalyst) in asymmetric synthesis and catalysis, the synthesis of new chiral ligands (amino alcohols, diamines, phosphines, NHC,…) derived from biomass products and their applications for asymmetric catalysis, and the preparation of molecules or molecular scaffolds of biological interest.

Vinylogous and stereoselective domino synthesis of pyrano[2,3-c]pyrroles from alkylidene meldrum’s acids. M. Savchuk, G. Vo-Thanh, S. Oudeyer, H. Beucher, J.-F. Brière, Organic & Biomolecular Chemistry, 2024, 22, 2948-2952

Enantioselective Acyl-Transfer/Protonation Reactions with Designed Chiral Thiourea-Iminophosphorane Catalysts. J. Kong, C. Lacroix, C. Bournaud, Y. Yamashita, S. Kobayashi, G. Vo-Thanh, Adv. Synth. Cata, 2024, 366, 1101-1106

An Organocatalytic and Stereoselective Vinylogous Domino Process towards Thiochromans. P. Milbeo, A. Lebrêne, M. Savchuk, G. Vo-Thanh, S. Oudeyer, H. Beucher, J.-F. Brière, Chemistry—A European Journal, 2023

Electrochemical Synthesis of Hetero[7]helicenes Containing Pyrrole and Furan Rings via an Oxidative Heterocoupling and Dehydrative Cyclization Sequence. M. S. H. Salem, M. I. Khalid, M. Sako, K. Higashida, C. Lacroix, M. Kondo, R. Takishima, T. Taniguchi, M. Miura, G. Vo-Thanh, H. Sasai, S. Takizawa, Adv. Synth. Catal, 2023, 365, 373-380

Vinblastine loaded on graphene quantum dots and its anticancer applications. T. H. Au, B. N. Nguyen, P. H. Nguyen, S. Pethe, G. Vo-Thanh, T. H. Vu Thi, Journal of Microencapsulation, 2022, 39, 239-251

Bifunctional N-Heterocylic Carbene-Catalyzed Highly Enantioselective Trans-Cyclopentannulation of Enals and Enones via Homoenolate. Z. Jiang, M. Toffano, G. Vo-Thanh, C. Bournaud, ChemCatChem, 2021, 13, 712-717

Enantioselective Hydrophosphonylation of N-Boc Imines using Chiral Guanidine–Thiourea Catalysts. L. Chassillan, Y. Yamashita, W.-J. Yoo, M. Toffano, R. Guillot, S. Kobayashi, G. Vo-Thanh, Org. Biomol. Chem., 2021, 19, 10560-10564

Auto Tandem Catalysis: Asymmetric Vinylogous Cycloaddition / Kinetic Resolution Sequence for the Enantioselective Synthesis of Spiro-Dihydropyranone from Benzylidene Meldrum’s Acid. M. Toffano, R. Guillot, C. Bournaud, J.-F. Brière, G. Vo-Thanh, Advanced Synthesis & Catalysis, 2021, 363, 4452-4458

Structural modification and biological activity studies of Tagitinin C and its derivatives. T. H. Au, C. Skarbek, S. Pethe, R. Labruère, J.-P. Baltaze, T. P. Hoa Nguyen, T. T. H. Vu, G. Vo-Thanh, Tetrahedron, 2021, 92, 132248

Alkylidene Meldrum’s Acids as Novel Platforms for the Vinylogous Synthesis of Dihydropyranones. G. Vo-Thanh, S. Wittmann, T. Martzel, C.-T. Pham Truong, M. Toffano, S. Oudeyer, R. Guillot, C. Bournaud, V. Gandon, J.-F. Brière, Angewandte Chemie International Edition, 2021, 60, 11110-11114

Using solid carriers impregnated with ammonium ionic liquids for platinum(IV) recovery from chloride solutions. T. L. T. Bui, T. N. H. Uong, K. D. Nguyen, T. K. D. Hoang, G. Vo-Thanh, Korean Journal of Chemical Engineering, 2020, 37, 2262-2272

Vanadium(V) Complex-Catalyzed One-Pot Synthesis of Phenanthridines via a Pictet-Spengler Dehydrogenative Aromatization Sequence. M. Sako, R. Losa, T. Takiishi, G. Vo-Thanh, S. Takizawa, H. Sasai, Catalysts, 2020, 10, 860

Dialkyl Imidazolium Acetate Ionosilica as efficient and Recyclable Organocatalyst for Cyanosilylation Reactions of Ketone. T. D. Tran, A. D. Rodrigues, G. Vo-Thanh, P. Peter Hesemann, Green Energy & Environment, 2020, 5, 130-137

Synergetic catalysis for one-pot bis-alkoxycarbonylation of terminal alkynes over Pd/Xantphos-Al(OTf)3 bi-functional catalytic system. W.-D. Guo, L. Liu, S.-Q. Yang, X.-C. Chen, Y. Lu, G. Vo-Thanh, Y. Liu, ChemCatChem, 2020, 12, 1376-1384

Chiral catalysts derived from biomass: design, synthesis and applications in asymmetric catalysis. T. T. D. Ngo, K.-D. Huynh, H. Ibrahim, T. H. Nguyen, C. Bournaud, M. Toffano, G. Vo-Thanh, Vietnam Journal of Chem, 2019, 57, 670-680

Divergent Synthesis of 1,2-Benzo[e]thiazine and Benzo[d]thiazole Analogues Containing a S-Trifluoromethyl Sulfoximine Group: Preparation and New Properties of the Adachi Reagent. A.-L. Barthelemy, E. Anselmi, T.-N. Le, G. Vo-Thanh, R. Guillot, K. Miqueu, E. Magnier, JOURNAL OF ORGANIC CHEMISTRY, 2019, 84, 4086-4094

An efficient and recyclable ionic diphosphine-based Ir-catalyst for hydroaminomethylation of olefins with H2O as hydrogen source. H. Liu, D. Yang, D.-L. Wang, P. Wang, Y. Lu, G. Vo-Thanh, Y. Liu, Chemical Communications, 2018, 54, 7979-7982

Novel Class of Reversible Chiral Ionic Liquids Derived from Natural Amino Acids: Synthesis and Characterization. L. Bouchardy, V. Rodriguez-Ruiz, F.-D. Boyer, C. Bournaud, M. Toffano, P. Judeinstein, G. Vo-Thanh, ChemistrySelect, 2018, 3, 958-962

Amphiphilic Zwitterionic phosphine based Au(I)-complex as efficient and recyclable catalyst for hydration of alkynes free of additional additives. X. Chen, X. Ye, W.-Y. Liang, Q. Zhou, G. Vo-Thanh, Y. Liu, Molecular Catalysis, 2018, 448, 171-176

Imidazolium based Ionic liquids as efficient reagents for lignin C-O bond cleavage. M. Thierry, A. Majira, B. Pégot, L. Cezard, F. Bourdreux, G. Clément, F. Perreau, S. Boutet-Mercey, P. Diter, G. Vo-Thanh, C. Lapierre, P.-H. Ducrot, E. Magnier, S. Baumberger, B. Cottyn, ChemSusChem, 2018, 11, 439-448

Fast and Efficient Hantzsch Synthesis using Acid-activated and Cation-exchanged Montmorillonite Catalysts under Solvent-free Microwave Irradiation Conditions. D. D. Pham, N. T. Le, G. Vo-Thanh, ChemistrySelect, 2017, 2, 12041-12045

Chiral Organocatalyzed Intermolecular Rauhut–Currier Reaction of Nitroalkenes with Ethyl Allenoate. S. Takizawa, M. Sako, K. Kishi, M. Shigenobu, G. Vo-Thanh, H. Sasai, Chemical and Pharmaceutical Bulletin, 2017, 65, 997-999

Efficient and Green Synthesis of 4H-pyran derivatives under Ultrasound Irradiation in the presence of K2CO3 supported on Acidic Montmorillonite. D. D. Pham, G. Vo-Thanh, N. T. Le, Synthetic Communications, 2017, 47, 1684-1691

S-Trifluoromethyl Sulfoximine as a Directing Group in Ortho-Lithiation Reaction toward Structural Complexity. T.-N. Le, P. Diter, B. Pégot, C. Bournaud, M. Toffano, R. Guillot, G. Vo-Thanh, E. Magnier, Org. Lett., 2016, 18, 5102-5105

Organocatalyzed [4+2] Annulation of All-Carbon Tetrasubstituted Alkenes with Allenoates: Synthesis of Highly Functionalized 2H- and 4H-Pyran Derivatives. T.-T.-D. Ngo, K. Kishi, M. Sako, M. Shigenobu, C. Bournaud, M. Toffano, R. Guillot, J.-P. Baltaze, S. Takizawa, H. Sasai, G. Vo-Thanh, ChemistrySelect, 2016, 1, 5414-5420

Biosourced Ligands from Isosorbide for the Ethylation of Aldehydes or Alkynylation of Imines. K.-D. Huynh, H. Ibrahim, L. Bouchardy, C. Bournaud, E. Kolodziej, M. Toffano, G. Vo-Thanh, Asian Journal of Organic Chemistry, 2016, 1242-1246

Phosphine–Thiourea-Organocatalyzed Asymmetric C−N and C−S Bond Formation Reactions. T.-T.-D. Ngo, T.-H. Nguyen, C. Bournaud, R. Guillot, M. Toffano, G. Vo-Thanh, Asian Journal of Organic Chemistry, 2016, Volume 5, Issue 7, 895–899

Synthesis of Novel Triazolo Cyclobutane Nucleoside Analogues. T.-T.-T. Tran, N.-T. Ngo, T.-H. Dinh, G. Vo-Thanh, S. Legoupy, Bull. Korean Chem. Soc, 2015, 36, 1390-1395

Functionalized S-perfluorinated sulfoximines: preparation and evaluation in catalytic process. T.-N. Le, P. Diter, B. Pégot, C. Bournaud, M. Toffano, R. Guillot, G. Vo-Thanh, Y. Yagupolskii, E. Magnier, Journal of Florine Chemistry, 2015, 179, 179-187

Synthesis and Characterization of New Chiral Azolinium Salts, Precursors to N-Heterocyclic Carbenes, Derived from l-Proline. A. Thomasset, L. Bouchardy, C. Bournaud, R. Guillot, M. Toffano, G. Vo-Thanh, Synthesis, 2014, 46, 242-250

Synthesis and Biological Evaluation of Febrifugine Analogues. T.-M.-H. Doan, G. Vo-Thanh, V.-H. Tran, V.-N. Vu, V.-L. Vu, C.-V. Le, T.-L. Nguyen, T.-D. Phi, B.-N. Truong, V.-M. Chau, V.-C. Pham, Natural Product Communications, 2014, 9, 1717-1720

Synthesis of febrifuginol analogues and evaluation of their biological activities. T.-M.-H. Doan, G. Vo-Thanh, V.-H. Tran, V.-N. Vu, V.-L. Vu, B.-N. Truong, T.-D. Phi, V.-M. Chau, V.-C. Pham, Tetrahedron Letters, 2014, 55, 6377-6380

Synthesis of chiral thiourea–phosphine organocatalysts derived from l-proline. T.-H. Nguyen, M. Toffano, C. Bournaud, G. Vo-Thanh, Tetrahedron Letters, 2014, 55, 6377-6380

First Isolation of Enantiopure Perfluoroalkylated Sulfilimines and Sulfoximines. T.-N. Le, E. Kolodziej, P. Diter, B. Pégot, C. Bournaud, M. Toffano, R. Guillot, G. Vo-Thanh, E. Magnier, CHIMIA International Journal for Chemistry, 2014, 68, 410-413

  • Roquette Research fund (2018-2020: 1 post-doc, 120 KE);
  • PEDR (Prime d’Encadrement Doctoral et de Recherche): 2016-2020 ;
  • Roquette Research fund (2017-2018: 1 post-doc, 65 KE);
  • Inter Labex Charm3at-Synorg Research fund (2017-2018: 60 KE);
  • Labex AAP Post-doc Research fund (2014: 55 KE);
  • Dexera Research fund (2014);
  • PES (Prime d’Excellence Scientifique) 2011-2015;
  • China Scholarship Council: 2017-2021, bourse de these;
  • China Fellowship Council : Echanges de chercheurs et doctorants (2011-2013 : 6 mois x3).
  • Japan Society for the Promotion of Science Fellowship (2011, 2013, 2015, 2016);
  • MoET Research fund (6 Ph.D scholarships: 2006, 2007, 2010, 2011, 2013, 2017);
  • PES (Prime d’Excellence Scientifique): 2006-2010 ;
  • BQR (Bonus Qualité Recherche) 2009, UPSud ;
  • BQP (Bonus Qualité Pédagogique), 2008, UPSud ;
  • PRESUPSud Research fund (2010, 2012 : 1 post-doc);
  • CEM Research Fund (2009-2011: 1 post-doc);
  • Interchim Research Fund (2007-2010: 1 thèse de doctorat et 1 CDD d’un an);
  • The Institute of Industrial Chemistry Award for creative work in Green Chemistry’ 2009.
  • Word Top-50 Most Cited Articles in 2004-2007’:ACS National Meeting in Boston 2007.
  • ‘Tetrahedron Letters Most Cited Paper 2003-2006 Award’, 2004, 45, 6425-6428
  • CNRS Research Fellowship (1998-1999)
  • Sanofi Postdoctoral Fellowship (1997-1998)
  • National Institute of Health Postdoctoral Fellowship (1997-1998)
  • Aventis Medicinal Chemistry Graduate Research Fellowship (1994-1997)