Mixed hybridization systems : Towards the "after C60"
Axis 3 — Giant calixarenes : a new family of macromolecular objects
Associate researcher : Cyril Martini (NOVECAL)
As a part of our research program devoted to the study of calixarene chemistry, we discovered that some specifically functionalised phenols allows for the formation of very large calixarene-type cyclic oligomers, containing up to 100 phenolic sub-units. These unprecedented « giant calixarenes » are easily obtained according to simple one or two-steps processes.
Synthesis of giant calixarenes
These giant calixarenes are obtained in high yields, and their synthesis was upscaled up to a 500g amounts (laboratory scale). They were characterized by a full set of analytical tools (NMR, SEC, SEC-MALS, MALDI-MS, etc…).
Surprisingly, they can also be obtained in the solid state, without any kind of stirring/grinding mechanism. This points to a new solid-state organic chemistry.
This new family of macromolecular objects opens promising perspectives in such diverse areas as materials reinforcement, vectorisation, single molecule micellar objects etc…
Characterization of giant calixarenes
Giant Calixarenes: A New Family of Macromolecular Objects. V. Guérineau, M. Rollet, S. Viel, B. Lepoittevin, L. Costa, P. Saint-Aguet, R. Laurent, Ph. Roger, D. Gigmes, C. Martini, V. Huc (Accepté) Nature Communication
Synthèse à hauts rendements de p-(benzyloxy)calix[6,7,8]arènes. C. Martini, V. Huc (2013) WO/2013/088056
Procédé de préparation à hauts rendements de p-(R)calix[9-20]arènes. C. Martini, V. Huc (2014) 14/51660
Procédé de préparation à hauts rendements de p-(R)calixarènes géants. C. Martini, V. Huc (2014) WO/2014/033407
Procédé de préparation à hauts rendements de p-(R-oxy)calix[9-20]arènes. C. Martini, V. Huc (2014) WO/2014/033406
Last update on 11.13.2019