Institut de Chimie Moléculaire et des Matériaux d'Orsay

Jean-Pierre Mahy

Bât. 420, bureau 113 – LCBB – ICMMO
Université Paris-Saclay
Rue du doyen Georges Poitou
91405 Orsay Cedex

+33 1 69 15 74 21

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An artificial metalloprotein with metal-adaptive coordination sites and Ni-dependent quercetinase activity. M. Beaumet, A. Dose, A. Bräuer, J.-P. Mahy, W. Ghattas, M. Groll, C. R. Hess, J. Inorg. Biochem., 2022, 111914

Diels-alderases artificielles au service de la chimie verte. W. Ghattas, J.-P. Mahy, R. Ricoux, A. J. Simaan, M. Réglier, Techniques de l'ingénieur, 2021, IN404, 1-25

Artificial enzymes for Diels-Alder reactions. W. Ghattas, J.-P. Mahy, M. Réglier, A. J. Simaan, ChemBioChem, 2021, 22, 443-459

Recent progress in the development of new artificial metalloenzymes as biocatalysts for selective oxidations and Diels-Alder reaction - Mini-Review. F. Avenier, W. Ghattas, R. Ricoux, J.-P. Mahy, Vietnam J. Chem., 2020, 58, 423-433

Binding of a Soluble meso-Tetraarylporphyrin to Human Galectin-7 Induces Oligomerization and Modulates Its Pro-Apoptotic Activity. Y. López De Los Santos, D. N. Bernard, P. Egesborg, M. Létourneau, C. Lafortune, M. J. Cuneo, A. Urvoas, D. Chatenet, J.-P. Mahy, Y. St-Pierre, R. Ricoux, N. Doucet, Biochemistry, 2020, 59, 4591-4600

Bioinspired Symmetrical and Unsymmetrical Diiron Complexes for Selective Oxidation Catalysis with Hydrogen Peroxide. A. Trehoux, R. Guillot, M. Clémancey, G. Blondin, J.-M. Latour, J.-P. Mahy, F. Avenier, Dalton Trans., 2020, 49, 16657-16661

An artificial hemoprotein with inducible peroxidase- and monooxygenase-like activities. J.-P. Mahy, K. Kariyawasam, T. Di Meo, F. Hammerer, M. Valerio-Lepiniec, G. Sciortino, J.-D. Maréchal, P. Minard, A. Urvoas, R. Ricoux, Chem. Eur. J., 2020, 26, 14929-14937

Characterization in Aqueous Medium of an FMN Semiquinone Radical Stabilized by the Enzyme-Like Microenvironment of a Modified Polyethyleneimine. Y. Chevalier, Y. L. T. Ki, C. Herrero, D. L. Nouen, J.-P. Mahy, J.-P. Goddard, F. Avenier, Org. Biomol. Chem., 2020, 18, 4386-4389

Aerobic Oxidation Catalyzed by Polyoxometalates Associated to an Artificial Reductase at Room Temperature and in Water. A. Naim, Y. Chevalier, Y. Bouzidi, P. Gairola, P. Mialane, A. Dolbecq-Bastin, F. Avenier, J.-P. Mahy, Inorg. Chem. Frontiers, 2020, 7, 2362-2369

Artificial iron hydrogenase made by covalent grafting of Knölker's complex into xylanase: Application in asymmetric hydrogenation of an aryl ketone in water. K. Kariyawasam, W. Ghattas, Y. L. D. L. Santos, N. Doucet, S. Gaillard, J.-L. Renaud, F. Avenier, J.-P. Mahy, R. Ricoux, Biotechnol. Appl. Biochem., 2020, 67, 563-573

Encapsulation of Microperoxidase-8 in MIL-101(Cr)-X Nanoparticles: Influence of MOF Functionalization on Enzymatic Immobilization and Catalytic Activity. E. Gkaniatsou, R. Ricoux, K. Kariyawasam, I. Stenger, B. Fan, N. Ayoub, S. Salas, G. Patriarche, C. Serre, J.-P. Mahy, N. Steunou, C. Sicard, ACS Appl. Nano Mater., 2020, 3, 3233-3243

Recent advances in the field of artificial hemoproteins: new efficient eco-compatible biocatalysts for nitrene- oxene- and carbene-transfer reactions. K. Kariyawasam, R. Ricoux, J.-P. Mahy, J. Porphyrins Phthalocyanines, 2019, 23, 1273-1285

CuII-Containing 1-Aminocyclopropane Carboxylic Acid Oxidase Is an Efficient Stereospecific Diels–Alderase. W. Ghattas, V. Dubosclard, S. Tachon, M. Beaumet, R. Guillot, M. Réglier, A. J. Simaan, J.-P. Mahy, Angew. Chem. Int. Ed., 2019, 58, 14605-14609

Enhancing microperoxidase activity and selectivity: immobilization in metal-organic frameworks. E. Gkaniatsou, C. Serre, J.-P. Mahy, N. Steunou, R. Ricoux, C. Sicard, J. Porphyrins Phthalocyanines, 2019, 23, 718-728

Functionalized Artificial Bidomain Proteins Based on an α-Solenoid Protein Repeat Scaffold: A New Class of Artificial Diels–Alderases. T. Di Meo, K. Kariyawasam, W. Ghattas, M. Valerio-Lepiniec, G. Sciortino, J.-D. Maréchal, P. Minard, J.-P. Mahy, A. Urvoas, R. Ricoux, ACS Omega, 2019, 4, 4437-4447

Selective Formation of an FeIVO or an FeIIIOOH Intermediate From FeII-H2O2 : Controlled Heterolytic vs Homolytic O-O Bond Cleavage by the Second Coordination Sphere. K. Cheaib, M. Q. E. Mubarak, K. Sénéchal-David, C. Herrero, R. Guillot, M. Clémancey, J.-M. Latour, S. D. Visser, J.-P. Mahy, F. Banse, F. Avenier, Angew. Chem. Int. Ed., 2019, 58, 854-858

Incorporation of a minimal nucleotide into DNA. P. Röthlisberger, F. Levi-Acobas, I. Sarac, R. Ricoux, J.-P. Mahy, P. Herdewijn, P. Marlière, M. Hollenstein, Tetrahedron Lett., 2018, 59, 4241-4244

Aerobic Baeyer-Villiger Oxidation Catalyzed by a Flavin-Containing Enzyme Mimic in Water. Y. Chevalier, Y. L. T. Ki, D. L. Nouen, J.-P. Mahy, J.-P. Goddard, F. Avenier, Angew. Chem. Intern. Ed., 2018, 57, 16412-16415

Enzyme encapsulation in mesoporous Metal-Organic Frameworks for selective biodegradation of harmful dye molecules. E. Gkaniatsou, C. Sicard, R. Ricoux, L. Benahmed, F. Bourdreux, Q. Zhang, C. Serre, J.-P. Mahy, N. Steunou, Angew. Chem. Intern. Ed., 2018, 57, 16141-16146

Receptor-based artificial metalloenzymes on living human cells. W. Ghattas, V. Dubosclard, A. Wick, A. Bendelac, R. Guillot, R. Ricoux, J.-P. Mahy, J. Am. Chem. Soc., 2018, 140, 8756-8762

Imidazolidine Ring Cleavage upon Complexation with First Row Transition Metals. K. Cheaib, C. Herrero, R. Guillot, F. Banse, J.-P. Mahy, F. Avenier, Eur. J. Inorg. Chem., 2017, 3884-3891

αRep A3: A versatile artificial scaffold for metalloenzyme design. T. Di Meo, W. Ghattas, C. Herrero, C. Velours, P. Minard, J.-P. Mahy, R. Ricoux, A. Urvoas, Chem. Eur. J., 2017, 23, 10156-10166

Elucidating the light-induced charge accumulation in an artificial analogue of methane monooxygenase enzymes using time-resolved x-ray absorption spectroscopy. D. Moonshiram, A. Picon, Á. Vázquez-Mayagoitia, X. Zhang, M.-F. Tu, P. Garrido-Barros, J.-P. Mahy, F. Avenier, A. Aukauloo, Chem. Commun., 2017, 53, 2725-2728

Metal–organic frameworks: a novel host platform for enzymatic catalysis and detection. E. Gkaniatsou, C. Sicard, R. Ricoux, J.-P. Mahy, N. Steunou, C. Serre, Mater. Horiz., 2017, 4, 55-63

Photoassisted Oxidation of Sulfides Catalyzed by Artificial Metalloenzymes Using Water as an Oxygen Source. C. Herrero, N. Nguyen-Thi, F. Hammerer, F. Banse, D. Gagné, N. Doucet, J.-P. Mahy, R. Ricoux, Catalysts, 2016, 6, 202

Reduction of a Tris(picolyl)amine Copper(II) Complex by an Polymeric Flavo-Reductase model in Water. K. Cheaib, Y. Roux, C. Herrero, A. Trehoux, F. Avenier, J.-P. Mahy, Dalton Trans., 2016, 45, 18098-18101

A growing family of o2 activating dinuclear iron enzymes with key catalytic diiron(III)-peroxo intermediates: biological systems and chemical models. A. Trehoux, J.-P. Mahy, F. Avenier, Coord. Chem. Rev., 2016, 322, 142-158

Artificial Metalloenzymes with the Neocarzinostatin Scaffold: Toward a Biocatalyst for the Diels–Alder Reaction. W. Ghattas, L. Cotchico-Alonso, J.-D. Maréchal, A. Urvoas, M. Rousseau, J.-P. Mahy, R. Ricoux, ChemBioChem, 2016, 17, 433-440

Oxidation catalysis via visible-light water activation of a [Ru(bpy)3]2+ chromophore BSA-metallocorrole couple. C. Herrero, A. Quaranta, R. Ricoux, A. Trehoux, A. Mahammed, Z. Gross, F. Banse, J.-P. Mahy, Dalton Trans., 2016, 45, 706-710

Bio-inspired electron-delivering system for reductive activation of dioxygen at metal centres towards artificial flavoenzymes. Y. Roux, R. Ricoux, F. Avenier, J.-P. Mahy, Nature Communications, 2015, 6, 8509

An Artificial Enzyme Made by Covalent Grafting of an FeII Complex into β-Lactoglobulin: Molecular Chemistry, Oxidation Catalysis, and Reaction-Intermediate Monitoring in a Protein. C. Buron, K. Sénéchal-David, R. Ricoux, J.-P. Le Caër, V. Guérineau, P. Méjanelle, R. Guillot, C. Herrero, J.-P. Mahy, F. Banse, Chem. Eur. J., 2015, 21, 12188-12193

Synthesis and characterization of [Fe(BPMEN)ACC]SbF₆: a structural and functional mimic of ACC-oxidase. Y. Roux, W. Ghattas, F. Avenier, R. Guillot, A. J. Simaan, J.-P. Mahy, Dalton Trans., 2015, 44, 5966-5968

From "hemoabzymes" to "hemozymes": towards new biocatalysts for selective oxidations. J.-P. Mahy, J.-D. Maréchal, R. Ricoux, Chemical Communications, 2015, 51, 2476-2494

Catalytic oxidation of dibenzothiophene and thioanisole by a diiron(III) complex and hydrogen peroxide. A. Trehoux, Y. Roux, R. Guillot, J.-P. Mahy, F. Avenier, Journal of Molecular Catalysis A: Chemical, 2015, 396, 40-46

Various strategies for obtaining oxidative artificial hemoproteins with a catalytic oxidative activity: from "Hemoabzymes" to "Hemozymes"? J.-P. Mahy, J.-D. Maréchal, R. Ricoux, J. Porphyrins Phthalocyanines, 2014, 18, 1063-1092

Neocarzinostatin-based hybrid biocatalysts with a RNase like activity. A. Urvoas, W. Ghattas, J.-D. Maréchal, F. Avenier, F. Bellande, W. Mao, R. Ricoux, J.-P. Mahy, Bioorg. Med. Chem., 2014, 22, 5678-5686

Catalytic C-H Amination: A Reaction Now Accessible to Engineered Natural Enzymes. J.-P. Mahy, J. Ciesielski, P. Dauban, Angew. Chem. Intern. Ed., 2014, 53, 6862-6864

Neocarzinostatin-based hybrid biocatalysts for oxidation reactions. E. Sansiaume-Dagousset, A. Urvoas, K. Chelly, W. Ghattas, J.-D. Maréchal, J.-P. Mahy, R. Ricoux, Dalton Trans., 2014, 43, 8344-8354

A unique 1-amino-1-cyclopropane carboxylate cupric-cryptate hosting sodium. W. Ghattas, R. Ricoux, H. Korri-Youssoufi, R. Guillot, E. Riviere, J.-P. Mahy, Dalton Trans., 2014, 43, 7708-7711