Emilie Lesur
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Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β-Ketoesters Containing an Alkyne Using the Noyori Catalyst. P. Rollando, E. Lesur, D. Urban, G. Doisneau, D. Guianvarc’H, Y. Bourdreux, European Journal of Organic Chemistry, 2025, n/a, e202500642
Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria. E. Lesur, Y. Zhang, N. Dautin, C. Dietrich, I. Li De La Sierra-Gallay, L. A. Augusto, P. Rollando, N. Lazar, D. Urban, G. Doisneau, F. Constantinesco-Becker, H. Van Tilbeurgh, D. Guianvarc’H, Y. Bourdreux, N. Bayan, Journal of Biological Chemistry, 2025, 301, 108243
Bioorthogonal Monomycolate of Trehalose Disclosed the O-Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum. C. Labarre, Y. Zhang, E. Lesur, M. Ley, L. Sago, C. Dietrich, C. De Sousa-D’Auria, F. Constantinesco-Becker, A. Baron, G. Doisneau, D. Urban, G. Chevreux, D. Guianvarc’H, Y. Bourdreux, N. Bayan, ACS Chem. Biol., 2024, 19, 2359–2371
Synthesis of trehalose-based chemical tools for the study of the mycobacterial membrane. E. Lesur, P. Rollando, D. Guianvarc′h, Y. Bourdreux, Comptes Rendus. Chimie, 2023, online
Synthesis of chemical tools to label the mycomembrane of corynebacteria using a modified Iron (III) chloride-mediated protection of trehalose. M. Carlier, E. Lesur, A. Baron, A. Lemétais, K. Guitot, L. Roupnel, C. Dietrich, G. Doisneau, D. Urban, N. Bayan, J.-M. Beau, D. Guianvarc′h, B. Vauzeilles, Y. Bourdreux, Org. Biomol. Chem., 2022, 20, 1974-1981
Etudier la membrane des mycobactéries via une approche chémobiologique. E. Lesur, Y. Bourdreux, L'Actualité Chimique, 2021, 465, 63-64, https://new.societechimiquedefrance.fr/numero/fiche-n-87-etudier-la-membrane-des-mycobacteries-via-une-approche-chemobiologique-p63-n465/
First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria. E. Lesur, A. Baron, C. Dietrich, M. Buchotte, G. Doisneau, D. Urban, J.-M. Beau, N. Bayan, B. Vauzeilles, D. Guianvarc′h, Y. Bourdreux, Chem. Commun., 2019, 55, 13074-13077