Institut de Chimie Moléculaire et des Matériaux d'Orsay

1.2. Synthesis, biological and physico-chemical evaluations of antitumor prodrugs activated by reactive oxygen species

R. Labruère

Self-immolable benzeneboronate prodrugs by methylene quinone type removal

Context :
Cancer cell : highest level of oxidative stress: overproduction of ROS : H₂O₂

Strategy :
Targeting over-production of H₂O₂ for the design of new antitumoral therapies :

Participant :
Silvia Serra, Postdoc Ligue contre le Cancer (01/01/2016-31/12/2017)

Collaboration :
Thomas Le Saux, Ludovic Jullien, ENS Paris