Institut de Chimie Moléculaire et des Matériaux d'Orsay

Logo CP3A 1.jpg CP3A ORGANIC SYNTHESIS GROUP

Peptidomimetic Chemistry, Photochemistry, Alternative Processes

Claire M. GRISON

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«β/γ-Peptide manifolds designed as α-helix mimetics» under the supervision of Prof. David J. Aitken et du Dr. Sylvie Robin.

Publications

  • Conformational effects through hydrogen bonding in a constrained γ-peptide template: from intra-residue 7-membered rings to a gel-forming sheet structure. H. Awada, C. M. Grison, F. Charnay-Pouget, J.-P. Baltaze, F. Brisset, R. Guillot, S. Robin, A. Hachem, N. Jaber, D. Naoufal, O. Yazbeck, D. J. Aitken, J. Org. Chem., 2017, 82, 4819–4828.
  • An α-Helix-Mimicking 12,13-Helix: Designed α/β/γ-Foldamers as Selective Inhibitors of Protein–Protein Interaction. C. M. Grison, J. A. Miles, S. Robin, A. J. Wilson, D. J. Aitken, Angewandte Chemie International Edition, 2016, 55, 11096-11100.
  • 13-Helix folding of a β/γ-peptide manifold designed from a "minimal-constraint" blueprint. C. M. Grison, S. Robin, D. J. Aitken, Chem. Commun., 2016, 52, 7802-7805.
  • Metallophytes for organic synthesis: towards new bio-based selective protection/deprotection procedures. C. M. Grison, A. Velati, V. Escande, C. Grison, Environmental Science and Pollution Research, 2015, 22, 5686-5698.
  • The leguminous species Anthyllis vulneraria as a Zn-hyperaccumulator and eco-Zn catalyst resources. C. M. Grison, M. Mazel, A. Sellini, V. Escande, J. Biton, C. Grison, Environmental Science and Pollution Research, 2015, 22, 5667-5676.
  • The discovery of 9/8-ribbons, β/γ-peptides with curved shapes governed by a combined configuration-conformation code. D. J. Aitken, C. M. Grison, S. Robin, Chem. Commun., 2015, 51, 16233-16236.
  • Conformational preferences in the β-peptide oligomers of cis-2-amino-1-fluorocyclobutane-1-carboxylic acid. A. Hassoun, C. M. Grison, R. Guillot, T. Boddaert, D. J. Aitken, New J. Chem., 2015, 39, 3270-3279.
  • Pushing the limits of signal resolution to make coupling measurement easier. J. E. H. Pucheta, D. Pitoux, C. M. Grison, S. Robin, D. Merlet, D. J. Aitken, N. Giraud, J. Farjon, Chem Commun, 2015, 51, 7939-7942.
  • A simple synthesis of 2-keto-3-deoxy-D-erythro-hexonic acid isopropyl ester, a key sugar for the bacterial population living under metallic stress. C. M. Grison, B.-L. Renard, C. Grison, Bioorganic Chemistry, 2014, 52, 50-5