Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laurent Salmon

Build. 420, office 117 – LCBB – ICMMO
Université Paris-Saclay
Rue du doyen Georges Poitou
91405 Orsay Cedex

+33 1 69 15 63 11

Research themes : Theme 1

Teaching :

Last publications :

Novel N-substituted 5-phosphate-D-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: synthesis, structure-activity relationship and crystallographic studies. L. Ahmad, S. Plancqueel, N. Lazar, H. Korri-Youssoufi, I. Li de la Sierra-Gallay, H. van Tilbeurgh, L. Salmon, Bioorg. Chem. 2020, 102, 104048

Calibration of the dianionic phosphate group: Validation on the recognition site of the homodimeric enzyme phosphoglucose isomerase. M. Devillers, J.-P. Piquemal, L. Salmon, N. Gresh, J. Comput. Chem., 2020, 41, 839-854

Electrochemical detection of the human cancer biomarker ‘autocrine motility factor-phosphoglucose isomerase’ based on a biosensor formed with a monosaccharidic inhibitor. L. Ahmad, L. Salmon, H. Korri-Youssoufi, Sens. Actuators B Chem., 2019, 299, 126933

Bisphosphonate inhibitors of mammalian glycolytic aldolase. P. Heron, M. Abellán-Flos, L. Salmon, J. Sygusch, J. Med. Chem., 2018, 61, 10558-10572

Crystal Structure of Phosphomannose Isomerase from Candida albicans Complexed with 5‐Phospho‐D‐Arabinonhydrazide. L. Ahmad, S. Plancqueel, V. Dubosclard, N. Lazar, W. Ghattas, I. Li De La Sierra‐gallay, H. Van Tilbeurgh, L. Salmon, FEBS Lett., 2018, 592, 1667-1680

Carbohydrate-based electrochemical biosensor for detection of a cancer biomarker in human plasma. M. Devillers, L. Ahmad, H. Korri-Youssoufi, L. Salmon, Biosens. Bioelectron., 2017, 96, 178-185

Complexes of a Zn-metalloenzyme binding site with hydroxamate-containing ligands. A case for detailed benchmarkings of polarizable molecular mechanics/dynamics potentials when the experimental binding structure is unknown. N. Gresh, D. Perahia, B. De Courcy, J. Foret, C. Roux, L. El-Khoury, J.-P. Piquemal, L. Salmon, J. Comput. Chem., 2016, 37, 2770-2782

Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-Butanone-4-Phosphate Synthase from Vibrio cholerae. Z. Islam, A. Kumar, S. Singh, L. Salmon, S. Karthikeyan, J. Biol. Chem., 2015, 290, 11293-11308