Institut de Chimie Moléculaire et des Matériaux d'Orsay

Laurent Salmon

Professeur
Build. 670, office 1235 – LCBB – ICMMO - UMR 8182
Université Paris-Saclay
Bâtiment 670
17-19 Avenue des Sciences
91400 Orsay
FRANCE

+33 1 69 15 63 11
laurent.salmon@u-psud.fr
https://orcid.org/0000-0003-1946-8458


Research themes : Theme 1


Teaching :


Last publications :

Synthesis and kinetic evaluation of phosphomimetic inhibitors targeting type B ribose-5-phosphate isomerase from Mycobacterium tuberculosis. Stéphanie Courtiol-Legourd, Sandrine Mariano, Johanna Foret, Annette K. Roos, Sherry L. Mowbray, Laurent Salmon, Bioorg. Med. Chem. Lett. 2024, 102, 129666.

Nouveaux composés dipeptidiques, leur procédés de fabrication et une nouvelle application thérapeutique de composés dipeptidiques. L. Salmon, S. Pethe, R. Labruère, T. Naas, B. Iorga, M. Abellan-Flos, A. Diez-Martinez, M. Gayral, S. Oueslati, Univ. Paris-Saclay/CNRS/APHP, demande de brevet en France n° FR3111544 publiée le 24 décembre 2021, demande internationale PCT n° WO2021/255156 publié le 23 décembre 2021.

Novel N-substituted 5-phosphate-D-arabinonamide derivatives as strong inhibitors of phosphoglucose isomerases: synthesis, structure-activity relationship and crystallographic studies. L. Ahmad, S. Plancqueel, N. Lazar, H. Korri-Youssoufi, I. Li de la Sierra-Gallay, H. van Tilbeurgh, L. Salmon, Bioorg. Chem. 2020, 102, 104048

Calibration of the dianionic phosphate group: Validation on the recognition site of the homodimeric enzyme phosphoglucose isomerase. M. Devillers, J.-P. Piquemal, L. Salmon, N. Gresh, J. Comput. Chem., 2020, 41, 839-854

Electrochemical detection of the human cancer biomarker ‘autocrine motility factor-phosphoglucose isomerase’ based on a biosensor formed with a monosaccharidic inhibitor. L. Ahmad, L. Salmon, H. Korri-Youssoufi, Sens. Actuators B Chem., 2019, 299, 126933

Bisphosphonate inhibitors of mammalian glycolytic aldolase. P. Heron, M. Abellán-Flos, L. Salmon, J. Sygusch, J. Med. Chem., 2018, 61, 10558-10572

Crystal Structure of Phosphomannose Isomerase from Candida albicans Complexed with 5‐Phospho‐D‐Arabinonhydrazide. L. Ahmad, S. Plancqueel, V. Dubosclard, N. Lazar, W. Ghattas, I. Li De La Sierra‐gallay, H. Van Tilbeurgh, L. Salmon, FEBS Lett., 2018, 592, 1667-1680

Carbohydrate-based electrochemical biosensor for detection of a cancer biomarker in human plasma. M. Devillers, L. Ahmad, H. Korri-Youssoufi, L. Salmon, Biosens. Bioelectron., 2017, 96, 178-185

Complexes of a Zn-metalloenzyme binding site with hydroxamate-containing ligands. A case for detailed benchmarkings of polarizable molecular mechanics/dynamics potentials when the experimental binding structure is unknown. N. Gresh, D. Perahia, B. De Courcy, J. Foret, C. Roux, L. El-Khoury, J.-P. Piquemal, L. Salmon, J. Comput. Chem., 2016, 37, 2770-2782

Structural Basis for Competitive Inhibition of 3,4-Dihydroxy-2-Butanone-4-Phosphate Synthase from Vibrio cholerae. Z. Islam, A. Kumar, S. Singh, L. Salmon, S. Karthikeyan, J. Biol. Chem., 2015, 290, 11293-11308