Frederic Avenier
Education and positions
SInce 2022 : Professor at Université Paris-Saclay
2017 : Habilitation à Diriger des Recherches" from Université Paris Sud (September 03 2017)
Since 2009 : University Lecturer at Université Paris Sud
2008-2009 : ATER (Postdoc) at ENS Lyon, Bioorganic chemistry Lab (Prof. Hasserodt).
2004-2008 : Postdoc at the University of Cambridge, UK, Department of Biochemistry (Prof. Hollfelder).
2000-2003 : PhD in Molecular Chemistry at Université Joseph Fourier, Grenoble (Supervisor: Dr. Jean-Marc Latour).
Selected Publications
Selective Formation of an FeIVO or an FeIIIOOH Intermediate From FeII-H2O2: Controlled Heterolytic vsHomolytic O-O Bond Cleavage by the Second Coordination Sphere
Angew. Chem. Int. Ed. 2019, 58, 854-858
Aerobic Baeyer-Villiger Oxidation Catalyzed by a Flavin-Containing Enzyme Mimic in Water
Angew. Chem. Int. Ed. 2018, 57, 16412-16415
A Growing Family of O2 Activating Dinuclear Iron Enzymes with Key Catalytic Diiron(III)-peroxo Intermediates: Biological Systems and Chemical Models
Coord. Chem. Rev. 2016, 322, 142-158
Bio-inspired electron-delivering system for reductive activation of dioxygen at metal centres towards artificial flavoenzymes
Nature Communications 2015, 6, 8509
List of publications since 2013
Interplay of chloride levels and palladium(II)-catalyzed O-deallenylation bioorthogonal uncaging reactions. G. M. Dal Forno, E. Latocheski, C. D. Navo, B. L. Albuquerque, A. L. St John, F. Avenier, G. Jiménez-Osés, J. B. Domingos, Chem. Sci., 2024, 15, 4458-4465
Unprotected Amine Transfer Performed by Non-Heme Iron(II) Complexes. A. Boullé, A. Doumbia, J.-P. Mahy, F. Avenier, Chem. Commun., 2023, 59, 79-81
Experiments and DFT Computations Combine to Decipher Fe-Catalyzed Amidine Synthesis through Nitrene Transfer and Nitrile Insertion. G. Coin, P. Dubourdeaux, F. Avenier, R. Patra, L. Castro, C. Lebrun, P.-A. Bayle, J. Pécaut, G. Blondin, P. Maldivi, J.-M. Latour, ACS Catalysis, 2021, 11, 2253-2266
Recent progress in the development of new artificial metalloenzymes as biocatalysts for selective oxidations and Diels-Alder reaction - Mini-Review. F. Avenier, W. Ghattas, R. Ricoux, J.-P. Mahy, Vietnam J. Chem., 2020, 58, 423-433
Bioinspired Symmetrical and Unsymmetrical Diiron Complexes for Selective Oxidation Catalysis with Hydrogen Peroxide. A. Trehoux, R. Guillot, M. Clémancey, G. Blondin, J.-M. Latour, J.-P. Mahy, F. Avenier, Dalton Trans., 2020, 49, 16657-16661
Characterization in Aqueous Medium of an FMN Semiquinone Radical Stabilized by the Enzyme-Like Microenvironment of a Modified Polyethyleneimine. Y. Chevalier, Y. L. T. Ki, C. Herrero, D. L. Nouen, J.-P. Mahy, J.-P. Goddard, F. Avenier, Org. Biomol. Chem., 2020, 18, 4386-4389
Aerobic Oxidation Catalyzed by Polyoxometalates Associated to an Artificial Reductase at Room Temperature and in Water. A. Naim, Y. Chevalier, Y. Bouzidi, P. Gairola, P. Mialane, A. Dolbecq, F. Avenier, J.-P. Mahy, Inorg. Chem. Frontiers, 2020, 7, 2362-2369
Artificial iron hydrogenase made by covalent grafting of Knölker's complex into xylanase: Application in asymmetric hydrogenation of an aryl ketone in water. K. Kariyawasam, W. Ghattas, Y. L. D. L. Santos, N. Doucet, S. Gaillard, J.-L. Renaud, F. Avenier, J.-P. Mahy, R. Ricoux, Biotechnol. Appl. Biochem., 2020, 67, 563-573
Selective Formation of an FeIVO or an FeIIIOOH Intermediate From Iron(II) and H2O2 : Controlled Heterolytic versus Homolytic Oxygen-Oxygen Bond Cleavage by the Second Coordination Sphere. K. Cheaib, M. Q. E. Mubarak, K. Sénéchal-David, C. Herrero, R. Guillot, M. Clémancey, J.-M. Latour, S. D. Visser, J.-P. Mahy, F. Banse, F. Avenier, Angew. Chem. Int. Ed., 2019, 58, 854-858
Aerobic Baeyer-Villiger Oxidation Catalyzed by a Flavin-Containing Enzyme Mimic in Water. Y. Chevalier, Y. L. T. Ki, D. L. Nouen, J.-P. Mahy, J.-P. Goddard, F. Avenier, Angew. Chem. Int. Ed., 2018, 57, 16412-16415
Imidazolidine Ring Cleavage upon Complexation with First Row Transition Metals. K. Cheaib, C. Herrero, R. Guillot, F. Banse, J.-P. Mahy, F. Avenier, Eur. J. Inorg. Chem., 2017, 3884-3891
Redox Self-Adaptation of a Nitrene Transfer Catalyst to the Substrate Needs. E. Gouré, D. Senthilnathan, G. Coin, F. Albrieux, F. Avenier, P. Dubourdeaux, C. Lebrun, P. Maldivi, J.-M. Latour, Angew. Chem. Intern. Ed., 2017, 56, 4305-4309
Elucidating the light-induced charge accumulation in an artificial analogue of methane monooxygenase enzymes using time-resolved x-ray absorption spectroscopy. D. Moonshiram, A. Picon, Á. Vázquez-Mayagoitia, X. Zhang, M.-F. Tu, P. Garrido-Barros, J.-P. Mahy, F. Avenier, A. Aukauloo, Chem. Commun., 2017, 53, 2725-2728
Reduction of a Tris(picolyl)amine Copper(II) Complex by an Polymeric Flavo-Reductase model in Water. K. Cheaib, Y. Roux, C. Herrero, A. Trehoux, F. Avenier, J.-P. Mahy, Dalton Trans., 2016, 45, 18098-18101
A growing family of o2 activating dinuclear iron enzymes with key catalytic diiron(III)-peroxo intermediates: biological systems and chemical models. A. Trehoux, J.-P. Mahy, F. Avenier, Coord. Chem. Rev., 2016, 322, 142-158
Bio-inspired electron-delivering system for reductive activation of dioxygen at metal centres towards artificial flavoenzymes. Y. Roux, R. Ricoux, F. Avenier, J.-P. Mahy, Nature Communications, 2015, 6, 8509
Synthesis and characterization of [Fe(BPMEN)ACC]SbF₆: a structural and functional mimic of ACC-oxidase. Y. Roux, W. Ghattas, F. Avenier, R. Guillot, A. J. Simaan, J.-P. Mahy, Dalton Trans., 2015, 44, 5966-5968
Catalytic oxidation of dibenzothiophene and thioanisole by a diiron(III) complex and hydrogen peroxide. A. Trehoux, Y. Roux, R. Guillot, J.-P. Mahy, F. Avenier, Journal of Molecular Catalysis A: Chemical, 2015, 396, 40-46
Neocarzinostatin-based hybrid biocatalysts with a RNase like activity. A. Urvoas, W. Ghattas, J.-D. Maréchal, F. Avenier, F. Bellande, W. Mao, R. Ricoux, J.-P. Mahy, Bioorg. Med. Chem., 2014, 22, 5678-5686
Photoassisted Generation of a Dinuclear Iron(III) Peroxo Species and Oxygen-Atom Transfer. F. Avenier, C. Herrero, W. Leibl, A. Desbois, R. Guillot, J.-P. Mahy, A. Aukauloo, Angew. Chem. Intern. Ed., 2013, 52, 3634-3637