Institut de Chimie Moléculaire
& des Matériaux d’OrsaY
ACCÈS

Notre adresse

Institut de Chimie Moléculaire et des Matériaux d’Orsay
Bâtiment 670, Université Paris-Saclay, UMR 8182
17 Avenue des Sciences
91400 Orsay – France

Pour venir à l’ICMMO

Situé sur le plateau de Saclay, l’ICMMO fait partie de la faculté des sciences d’Orsay. Vous pouvez venir à l’ICMMO en transports en commun ou en voiture. Voyez le plan du campus .

Par la route

En venant de Paris, deux possibilités :

  • Paris-Ouest : à la porte de Saint-Cloud prendre la N118, direction Chartres-Orléans, sortie 9, Centre Universitaire-Grandes Ecoles – Orsay-Le Guichet. Puis au rond-point, prendre la 2nde sortie Rue Louis de Broglie et tourner à droite sur l’Avenue des Sciences.
  • Paris-Sud : à partir de la Porte d’Orléans prendre l’autoroute A10 direction Bordeaux-Nantes, puis Chartres-Orléans, sortie Orsay-Bures. Emprunter la N118 jusqu’à la sortie 9, Centre Universitaire-Grandes Ecoles – Gif sur Yvette. Puis au rond-point, 1ère sortie Centre universitaire et au second rond-point, prendre la 3eme sortie Rue Louis de Broglie et tourner à droite sur l’Avenue des Sciences.

Pour le stationnement voir ici .

Par les transports en commun

Prendre le RER ligne B en direction de Saint-Rémy-les-Chevreuse, descendre à la station Le Guichet puis prendre le bus 4609 ou descendre à la station Orsay puis prendre le bus 4607 à Gare d’Orsay – l’Yvette.

Institut de Chimie Moléculaire et des Matériaux d Orsay
Bat 670
17 Av. des Sciences
91190 Orsay

Sandrine Deloisy

Teaching Researcher
MSCO
sandrine.deloisy@-Code to remove to avoid SPAM-universite-paris-saclay.fr
0169153236, room 3113
Sandrine Deloisy studied chemistry at the University of Paris-Sud/Paris-Saclay and obtained her PhD in 1994. Her doctoral research on the synthesis of new fluoroquinolones as potential antibacterial agents was carried out at the Institut de Chimie des Substances Naturelles (ICSN, Gif-sur-Yvette) under the supervision of Dr. G. Lukacs. Supported by the Alexander von Humboldt Foundation, she spent two years in Mainz (Germany) in the group of Prof. H. Kunz, where she developed the use of carbohydrates as chiral auxiliaries. Upon returning to France, she obtained a teaching position at the IUT of Orsay, first as an ATER and then as a Maître de Conférences (associate professor). In 1997, she joined Dr. R. Bloch’s group at the Institut de Chimie Moléculaire et des Matériaux d’Orsay (ICMMO), where she studied the application of furan Diels-Alder chemistry on solid support and developed the chemistry of 7-oxanorbornadienes. In 2009, she turned her research interests toward the synthesis of organosilicon compounds in collaboration with Dr. L. Blanco. Since 2014, she works in the group of Prof. D. J. Aitken on α-silyloxymalononitrile derivatives as Masked Acyl Cyanide reagents, contributing to the development of the one-pot multicomponent MAC methodology and its application to the stereoselective synthesis of complex amino acids and their derived peptides.

Journal articles

2026

Stefano Barranco, Dianya Fu, Angelo Frongia, Sandrine Deloisy, David J Aitken. Synthesis of C1-quaternary 1-(α-methylbenzylamino)cyclobutane derivatives. Tetrahedron Letters, 2026, 185, pp.156271. ⟨10.1016/j.tetlet.2026.156271⟩. ⟨hal-05840527⟩

2025

Maria Chiara Cabua, Xuefeng He, Francesco Secci, Sandrine Deloisy, David Aitken. Rapid Synthesis of anti ‐1,3‐Diamino‐4‐phenylbutan‐2‐ol Building Blocks via a Three‐Component Oxyhomologation and a Two‐Component Reducing System. ChemistryOpen, 2025, 14 (2), ⟨10.1002/open.202400279⟩. ⟨hal-05849039⟩

2024

Xuefeng He, Régis Guillot, Sandrine Deloisy, David Aitken. High anti Diastereoselectivity in a Tandem Oxyhomologation–Coupling Protocol for the Preparation of Amides and Peptides Incorporating α-Hydroxy β-Amino Acids. Organic Letters, 2024, 26 (11), pp.2207-2211. ⟨10.1021/ACS.ORGLETT.4C00370⟩. ⟨hal-05771643⟩

2022

Xuefeng He, Marie Buchotte, Régis Guillot, Sandrine Deloisy, David Aitken. A case study of the MAC (masked acyl cyanide) oxyhomologation of N , N -dibenzyl- l -phenylalaninal with anti diastereoselectivity: preparation of (2 S ,3 S )-allophenylnorstatin esters. Organic & Biomolecular Chemistry, 2022, 20 (8), pp.1769-1781. ⟨10.1039/D1OB02411F⟩. ⟨hal-05771350⟩

2019

Mathieu Esgulian, Marie Buchotte, Régis Guillot, Sandrine Deloisy, David Aitken. Reversal of Diastereoselectivity in a Masked Acyl Cyanide (MAC) Reaction: Synthesis of Protected erythro -β-Hydroxyaspartate Derivatives. Organic Letters, 2019, 21 (7), pp.2378-2382. ⟨10.1021/ACS.ORGLETT.9B00664⟩. ⟨hal-05771192⟩

2017

Mathieu Esgulian, Vincent Belot, Régis Guillot, Sandrine Deloisy, David Aitken. Studies on cyclization reactions of 3-amino-2,4-dihydroxybutanoic acid derivatives. Organic & Biomolecular Chemistry, 2017, 15 (6), pp.1453-1462. ⟨10.1039/C6OB02759H⟩. ⟨hal-05770991⟩

2013

Audrey Giros, Régis Guillot, Luis Blanco, Sandrine Deloisy. An Unusual and Diastereoselective Rearrangement during an Intramolecular Ene Reaction Involving a Disilane. European Journal of Organic Chemistry, 2013, 2013 (26), pp.5809-5813. ⟨10.1002/EJOC.201300849⟩. ⟨hal-05770800⟩
Nisrine Sultan, Régis Guillot, Luis Blanco, Sandrine Deloisy. Regioselective Preparation of 7-Oxanorborna-2,5-diene-2,3-dicarboxylic Acid Derivatives by the Diels-Alder Reaction: A Selective Access to Furans by Retro-Diels-Alder Reaction. Synthesis: Journal of Synthetic Organic Chemistry, 2013, 45 (14), pp.2018-2028. ⟨10.1055/S-0033-1338802⟩. ⟨hal-05770763⟩

2011

Adrien Soret, Christine Müller, Régis Guillot, Luis Blanco, Sandrine Deloisy. Short and efficient synthesis of 2H-pyrroles from 7-oxanorbornadiene derivatives. Tetrahedron, 2011, 67 (4), pp.698-705. ⟨10.1016/J.TET.2010.11.080⟩. ⟨hal-05769773⟩

2009

Sébastien Albert, Luis Blanco, Sandrine Deloisy. Solid-phase cleavage by a thermal retro-Diels-Alder reaction: preparation of a small β-substituted α,β-ethylenic aldehydes library. ARKIVOC – Online Journal of Organic Chemistry, 2009, 2009 (13), pp.78-96. ⟨10.3998/ark.5550190.0010.d07⟩. ⟨hal-05841178⟩ PDF

2007

Sandrine Deloisy, Adrien Soret, Régis Guillot, Gérard Rousseau, Luis Blanco. Stereoselective 1,3-Dipolar Cycloaddition of a Maleate Derivative with Azomethine Ylides Derived from α-Amino Esters: Synthesis of 3-Pyrrolines. SYNLETT, 2007, 2007 (08), pp.1284-1288. ⟨10.1055/S-2007-977449⟩. ⟨hal-05769630⟩
Sébastien Albert, Adrien Soret, Luis Blanco, Sandrine Deloisy. Soluble and polymer-supported 2- and 3-benzylated furans for the preparation of α,β-ethylenic carbonyl compounds. Tetrahedron, 2007, 63 (13), pp.2888-2900. ⟨10.1016/j.tet.2007.01.030⟩. ⟨hal-05841186⟩ PDF