Philippe Lesot

Journal articles

2026

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Vincent Chiapolino, François-Marie Moussallieh, Philippe Lesot, Boris Gouilleux. 19F−{1H} NMR spectroscopy in weakly orienting solvents for the enantiomeric resolution of fluorinated chiral drugs: The case of fluoxetine. Journal of Pharmaceutical Analysis, 2026, 16 (5), pp.101469. ⟨10.1016/j.jpha.2025.101469⟩. ⟨hal-05440323v2⟩

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Florian Rigoulet, Guillaume Dauvergne, Jean-Valère Naubron, Philippe Lesot, Christie Aroulanda, et al.. [¹H]/[²H] discriminated bianthryl atropisotopomers: enantiospecific syntheses from BINOL and direct multi-spectroscopic analyses of their isotopic chirality. Chemical Science, 2026, 17 (13), pp.6513-6523. ⟨10.1039/D5SC09200K⟩. ⟨hal-05484356v2⟩

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2025

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Warda Fella Belaid, Azeddine Dekhira, Philippe Lesot, Ouassila Ferroukhi. Development of Deep Learning Software to Improve HPLC and GC Predictions using a new Crown-ether based Mesogenic Stationary Phase and Beyond. Journal of Chromatography A, 2025, 1739, pp.465476. ⟨10.1016/j.chroma.2024.465476⟩. ⟨hal-04799963⟩

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Thomas Julien, Boris Gouilleux, Michael Reggelin, Philippe Lesot. Spatially Resolved ¹³C NMR Spectroscopy in Bimesophasic Samples Applied to Molecular Analysis in Orienting Media. Magnetic Resonance in Chemistry, 2025, 63 (9), pp.691 – 702. ⟨10.1002/mrc.70003⟩. ⟨hal-05198638⟩

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Thomas Julien, Boris Gouilleux, Bernard Rousseau, Michael Reggelin, Philippe Lesot. Deuterium NMR in Chiral Polymer‐Based Bimesophasic Lyotropic Mixtures: From the Demixing Process to Analytical Applications. Chemistry–Methods, 2025, 5 (6), pp.e202500011. ⟨10.1002/cmtd.202500011⟩. ⟨hal-05105756⟩

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Philippe Lesot, Han Sun. Anisotropic NMR Spectroscopy. Magnetic Resonance in Chemistry, 2025, 63 (10), pp.760-761. ⟨10.1002/mrc.70012⟩. ⟨hal-05352366⟩

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2024

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Boris Gouilleux, François-Marie Moussallieh, Philippe Lesot. Potential and Performance of Anisotropic 19F NMR for the Enantiomeric Analysis of Fluorinated Chiral Active Pharmaceutical Ingredients. Analyst, In press, 149, pp.3204-3213. ⟨10.1039/d4an00237g⟩. ⟨hal-04558310⟩

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Thomas Julien, Boris Gouilleux, Bernard Rousseau, Stefan Immel, Michael Reggelin, et al.. Spatially Resolved Anisotropic Natural Abundance Deuterium 2D-NMR Spectroscopy Using Bimesophasic Lyotropic Chiral Systems. Journal of Physical Chemistry Letters, 2024, 15 (7), pp.2089-2095. ⟨10.1021/acs.jpclett.3c03302⟩. ⟨hal-04471708⟩

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2022

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Christie Aroulanda, Philippe Lesot. Molecular enantiodiscrimination by NMR spectroscopy in chiral oriented systems: Concept, tools, and applications. Chirality, 2022, 34, pp.182-244. ⟨10.1002/chir.23386⟩. ⟨hal-03512385⟩

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Philippe Berdagué, Boris Gouilleux, Markus Noll, Stefan Immel, Michael Reggelin, et al.. Study and quantification of enantiodiscrimination power of four polymeric chiral LLCs using NAD 2D-NMR. Physical Chemistry Chemical Physics, 2022, 24 (12), pp.7338-7348. ⟨10.1039/D1CP04915A⟩. ⟨hal-03586878⟩

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Boris Gouilleux, Francois-Marie Moussallieh, Philippe Lesot. Anisotropic 1H STD‐NMR Spectroscopy: Exploration of Enantiomer‐Polypeptide Interactions in Chiral Oriented Environments. ChemPhysChem, 2022, 24 (4), pp.e202200508. ⟨10.1002/cphc.202200508⟩. ⟨hal-03800520⟩

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2021

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Philippe Lesot, Philippe Berdagué, Virginie Silvestre, Gérald Remaud. Exploring the enantiomeric 13C position-specific isotope fractionation: challenges and anisotropic NMR-based analytical strategy. Analytical and Bioanalytical Chemistry, 2021, 413 (25), pp.6379-6392. ⟨10.1007/s00216-021-03599-8⟩. ⟨hal-03409628⟩

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2020

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Boris Gouilleux, Abdelkrim Meddour, Philippe Lesot. 2H QUOSY 2D-NMR Experiments in Weakly Aligning Systems: From the Conventional to the UF Approach. ChemPhysChem, 2020, 21, pp.1548-1563. ⟨10.1002/cphc.202000336⟩. ⟨hal-02623845⟩

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Philippe Lesot, Roberto R. Gil, Philippe Berdague, Armando Navarro-Vázquez. Deuterium Residual Quadrupolar Couplings: Crossing the Current Frontiers in the Relative Configuration Analysis of Natural Products. Journal of Natural Products, 2020, 83 (10), pp.3141-3148. ⟨10.1021/acs.jnatprod.0c00745⟩. ⟨hal-02949550⟩

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Philippe Lesot. Determination of the natural deuterium distribution of fatty acids by application of 2H 2D-NMR in liquid crystals: fundamentals, advances, around and beyond. Liquid Crystals, 2020, 47 (13), pp.1889-1910. ⟨10.1080/02678292.2019.1613685⟩. ⟨hal-02308723⟩

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Timothée Naret, Philippe Lesot, Andrew Puente, Prasad Polavarapu, David-Alexandre Buisson, et al.. Chemical Synthesis of [ 2 H]-Ethyl Tosylate and Exploration of Its Crypto-optically Active Character Combining Complementary Spectroscopic Tools. Organic Letters, 2020, 22 (22), pp.8846-8849. ⟨10.1021/acs.orglett.0c03219⟩. ⟨hal-02987518v2⟩

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Alberto Palazzolo, Timothée Naret, Marion Daniel‐bertrand, David‐alexandre Buisson, Simon Tricard, et al.. Tuning the Reactivity of a Heterogeneous Catalyst using N‐Heterocyclic Carbene Ligands for C−H Activation Reactions. Angewandte Chemie International Edition, 2020, 59 (47), pp.20879-20884. ⟨10.1002/anie.202009258⟩. ⟨hal-03001484⟩

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Viktor Pfeifer, Marie Certiat, Donia Bouzouita, Alberto Palazzolo, Sébastien Garcia-Argote, et al.. Hydrogen isotope exchange catalyzed by Ru nanocatalysts: labelling of complex molecules containing N-heterocycles and reaction mechanism insights. Chemistry – A European Journal, 2020, 26, pp.4988-4996. ⟨10.1002/chem.201905651⟩. ⟨cea-02487414⟩

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2019

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Philippe Lesot, Christie Aroulanda, Philippe Berdagué, Abdelkrim Meddour, Denis Merlet, et al.. Multinuclear NMR in Polypeptide Liquid Crystals: Three Fertile Decades of Methodological Developments and Analytical Challenges. Progress in Nuclear Magnetic Resonance Spectroscopy, 2019, Progress in Nuclear Magnetic Resonance Spectroscopy, 116, pp.85-154. ⟨10.1016/j.pnmrs.2019.10.001⟩. ⟨hal-02351278⟩

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Philippe Lesot, Philippe Berdagué, Abdelkrim Meddour, Alexander Kreiter, Markus Noll, et al.. 2H and 13C NMR-Based Enantiodetection Using Polyacetylene versus Polypeptide Aligning Media: Versatile and Complementary Tools for Chemists. ChemPlusChem, 2019, 84 (2), pp.144-153. ⟨10.1002/cplu.201800493⟩. ⟨hal-02308749⟩

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Philippe Lesot, Philippe Berdagué, Abdelkrim Meddour, Alexander Kreiter, Markus Noll, et al.. (Cover Profile) 2H and 13C NMR-Based Enantiodetection Using Polyacetylene versus Polypeptide Aligning Media: Versatile and Complementary Tools for Chemists. ChemPlusChem, 2019, pp.143-143. ⟨10.1002/cplu.201800584⟩. ⟨hal-02308742⟩

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Alain Louis-Joseph, Philippe Lesot. Designing and building a low-cost portable FT-NMR spectrometer in 2019: A modern challenge. Comptes Rendus. Chimie, 2019, 22, pp.695-711. ⟨10.1016/j.crci.2019.07.001⟩. ⟨hal-02308789⟩

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2018

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Longhui Gao, Serge Perato, Sébastien Garcia-Argote, Céline Taglang, Luis Miguel Martinez-Pietro, et al.. Ruthenium-catalyzed hydrogen isotope exchange of C(sp3)–H bonds directed by a sulfur atom. Chemical Communications, 2018, 54 (24), pp.2986-2989. ⟨10.1039/C8CC00653A⟩. ⟨hal-02308831⟩

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Philippe Lesot. À MRFood 2018, les sciences slimentaires rencontrent la spectroscopie par résonance magnétique!. Spectra Analyse, 2018, 323, pp.18-20. ⟨hal-02317627⟩

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Tristan Texier-Bonniot, Philippe Berdague, Richard J. Robins, Gérald Remaud, Philippe Lesot. Analytical contribution of deuterium 2D-NMR in oriented media to ²H/¹H isotopic characterization: the case of vanillin. Flavour and Fragrance Journal, 2018, 33 (3), pp.217-229. ⟨10.1002/ffj.3441⟩. ⟨hal-02140951⟩

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2017

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Emmy Auguste, Elodie Lucas, Laura Poigniez, Diviya Ramamurthy, Hélène Vaneeckhoutte, et al.. RMN de Paillasse à Transformée de Fourier: Le Renouveau de la RMN à Bas Champ.. Spectra Analyse, 2017, 315, pp.32-62. ⟨hal-02317538⟩

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Philippe Lesot. La “39th FGMR Annual Discussion Meeting 2017”: La Spectroscopie Magnétique Franco-Allemande dans tous ses “Etats”!. Spectra Analyse, 2017, pp.12-14. ⟨hal-02317591⟩

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Armando Navarro-Vázquez, Philippe Berdagué, Philippe Lesot. (Cover profile) Integrated Computational Protocol for the Analysis of Quadrupolar Splittings from Natural-Abundance Deuterium NMR Spectra in (Chiral) Oriented Media. ChemPhysChem, 2017, pp.1219-1219. ⟨10.1002/CPHC.201700454⟩. ⟨hal-02308843⟩

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Armando Navarro-Vázquez, Philippe Berdagué, Philippe Lesot. Integrated Computational Protocol for the Analysis of Quadrupolar Splittings from Natural-Abundance Deuterium NMR Spectra in (Chiral) Oriented Media. ChemPhysChem, 2017, 18 (10), pp.1252-1266. ⟨10.1002/cphc.201601423⟩. ⟨hal-02308835⟩

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2016

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Philippe Berdagué, Philippe Lesot, Jérémy Jacob, Valery T. Terwilliger, Claude Le Milbeau. Contribution of NAD 2D-NMR in liquid crystals to the determination of hydrogen isotope profile of methyl groups in miliacin. Geochimica et Cosmochimica Acta, 2016, 173, pp.337-351. ⟨10.1016/j.gca.2015.10.004⟩. ⟨insu-01225227⟩

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Philippe Lesot, Philippe Berdagué, Patrick Giraudeau. Detection of quadrupolar nuclei by ultrafast 2D NMR: exploring the case of deuterated analytes aligned in chiral oriented solvents. Chemical Communications, 2016, 52 (10), pp.2122-2125. ⟨10.1039/C5CC09409G⟩. ⟨hal-02314360⟩

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Zeinab Serhan, Christie Aroulanda, Philippe Lesot. Investigation of Solute-Fiber Affinity and Orientational Ordering of Norbornadiene Interacting with Two-Polypeptide Chiral Liquid Crystalline Solvents by Natural Abundance Deuterium (NAD) NMR. Journal of Physical Chemistry A, 2016, 120 (30), pp.6076-6088. ⟨10.1021/acs.jpca.6b04254⟩. ⟨hal-03004599⟩

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2015

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Philippe Berdagué, Jose-Enrique Herbert-Pucheta, Vishwajeet Jha, Armen Panossian, Frédéric Leroux, et al.. Multi-nuclear NMR of axially chiral biaryls in polypeptide orienting solvents: spectral discriminations and enantiorecognition mechanisms. New Journal of Chemistry, 2015, 39 (12), pp.9504-9517. ⟨10.1039/c5nj01434d⟩. ⟨hal-02314357⟩

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Philippe Lesot, Krzysztof Kazimierczuk, Julien Trébosc, Jean-Paul Amoureux, Olivier Lafon. Fast acquisition of multidimensional NMR spectra of solids and mesophases using alternative sampling methods. Magnetic Resonance in Chemistry, 2015, 53 (11), pp.927-939. ⟨10.1002/mrc.4290⟩. ⟨hal-02314353⟩

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Philippe Lesot, Christie Aroulanda, Herbert Zimmermann, Zeev Luz. Enantiotopic discrimination in the NMR spectrum of prochiral solutes in chiral liquid crystals. Chemical Society Reviews, 2015, 44 (8), pp.2330-2375. ⟨hal-02314352⟩

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Philippe Lesot. Chronique Littéraire: « NMR Spectroscopy in Liquid and Solids » de V. I. Bakhmutov. Spectra Analyse, 2015, 306, pp.16-16. ⟨hal-02317530⟩

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Philippe Lesot. Vladimir I. Bakhmutov: NMR spectroscopy in liquids and solids. Analytical and Bioanalytical Chemistry, 2015, 407 (29), pp.8625-8626. ⟨10.1007/s00216-015-9061-z⟩. ⟨hal-02314356⟩

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Ahmad Masarwa, Dennis Gerbig, Liron Oskar, Aharon Loewenstein, Hans Peter Reisenauer, et al.. Synthese und stereochemische Bestimmung von krypto-optisch-aktivem 2H6 -Neopentan. Angewandte Chemie, 2015, 127 (44), pp.13298-13302. ⟨10.1002/ange.201505349⟩. ⟨hal-02314354⟩

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Ahmad Masarwa, Dennis Gerbig, Liron Oskar, Aharon Loewenstein, Hans Peter Reisenauer, et al.. Synthesis and Stereochemical Assignment of Crypto-Optically Active 2-H6 -Neopentane. Angewandte Chemie International Edition, 2015, 54 (44), pp.13106-13109. ⟨10.1002/anie.201505349⟩. ⟨hal-03010704⟩

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2014

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Krzysztof Kazimierczuk, Olivier Lafon, Philippe Lesot. Criteria for sensitivity enhancement by compressed sensing: practical application to anisotropic NAD 2D-NMR spectroscopy. Analyst, 2014, 139 (11), pp.2702. ⟨10.1039/c4an00381k⟩. ⟨hal-02314349⟩

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Philippe Lesot, Zeev Luz, Christie Aroulanda, Herbert Zimmermann. NMR discrimination in nonrigid prochiral solutes dissolved in chiral liquid crystals: symmetry considerations. Magnetic Resonance in Chemistry, 2014, 52 (10), pp.581-594. ⟨10.1002/mrc.4110⟩. ⟨hal-02314350⟩

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Philippe Lesot, Olivier Lafon, Philippe Berdagué. Correlation 2D-NMR experiments involving both $^{13}$C and $^{2}$H isotopes in oriented media: methodological developments and analytical applications. Magnetic Resonance in Chemistry, 2014, 52 (10), pp.595-613. ⟨10.1002/mrc.4118⟩. ⟨hal-02314351⟩

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Philippe Lesot. RMN 2D DAN dans les CLC: de nouveaux outils pour l’étude du fractionnement isotopique naturel (²H/¹H) d’acides gras et de triglycérides. Spectra Analyse, 2014, 299 (62-72). ⟨hal-02317515⟩

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2013

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Monique Chan-Huot, Philippe Georges Julien Lesot, Philippe Pelupessy, Luminita Duma, Geoffrey Bodenhausen, et al.. On-the-fly’ Kinetics of Enzymatic Racemization using Deuterium NMR in DNA-based Chiral Oriented Media.. Analytical Chemistry, 2013, 85 (9), pp.4694-4697. ⟨10.1021/ac4004002⟩. ⟨hal-00807811⟩

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Assaad Nasr El Dine, Ali Khalaf, Danielle Gree, Olivier Tasseau, Fares Fares, et al.. Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains. Beilstein Journal of Organic Chemistry, 2013, 9, pp.1943-1948. ⟨10.3762/bjoc.9.230⟩. ⟨hal-00871797⟩

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James Emsley, Philippe Lesot, Geoffrey Luckhurst, Abdelkrim Meddour, Denis Merlet. Chiral solutes can seed the formation of enantiomorphic domains in a twist-bend nematic liquid crystal. Physical Review E : Statistical, Nonlinear, and Soft Matter Physics [2001-2015], 2013, 87 (4), ⟨10.1103/PhysRevE.87.040501⟩. ⟨hal-02311510⟩

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Patrick Judeinstein, Stéphanie Huet, Philippe Lesot. Multiscale NMR investigation of mesogenic ionic-liquid electrolytes with strong anisotropic orientational and diffusional behaviour. RSC Advances, 2013, 3 (37), pp.16604. ⟨10.1039/C3RA00025G⟩. ⟨hal-02311512⟩

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Aurélie Lemétais, Yann Bourdreux, Philippe Lesot, Jonathan Farjon, Jean-Marie Beau. Synthesis of a Mycobacterium tuberculosis tetra-acylated sulfolipid analogue and characterization of the chiral acyl chains using anisotropic NAD 2D-NMR spectroscopy.. Journal of Organic Chemistry, 2013, 78 (15), pp.7648-57. ⟨10.1021/jo4012255⟩. ⟨hal-00910978⟩

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2012

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Robert Berger, Jacques Courtieu, Roberto Gil, Christian Griesinger, Matthias Köck, et al.. Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?-A Critical Assessment. Angewandte Chemie International Edition, 2012, 51 (33), pp.8388-8391. ⟨10.1002/anie.201107626⟩. ⟨hal-02311507⟩

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Isabelle Billault, Alicia Le Du, Minale Ouethrani, Zeinab Serhan, Philippe Lesot, et al.. Probing substrate-product relationships by natural abundance deuterium 2D NMR spectroscopy in liquid-crystalline solvents: epoxidation of linoleate to vernoleate by two different plant enzymes. Analytical and Bioanalytical Chemistry, 2012, 402 (9), pp.2985-2998. ⟨10.1007/s00216-012-5748-6⟩. ⟨hal-02142700⟩

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Jacques Courtieu, Nicolas Giraud, Olivier Lafon, Philippe Lesot, Jean-Marc Nuzillard, et al.. La RMN en chimie organique. L’Actualité Chimique, 2012, 364-365, pp.30-41. ⟨hal-02317465⟩

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Philippe Lesot, Olivier Lafon. Experimental Detection of Achiral and Chiral Naturally Abundant 13 C– 2 H Isotopomers by 2D-NMR in Liquids and Chiral Oriented Solvents. Analytical Chemistry, 2012, 84 (10), pp.4569-4573. ⟨10.1021/ac300667n⟩. ⟨hal-02311506⟩

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Philippe Lesot, Olivier Lafon. Détection d’Isotopomères ²H-¹³C en Abondance Naturelle par RMN 2D Isotrope et Anisotrope, ou Comment Distinguer Expérimentalement une Molécule parmi 600 000?. Spectra Analyse, 2012, 287, pp.24-30. ⟨hal-02317494⟩

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Philippe Lesot, Zeinab Serhan, Christie Aroulanda, Isabelle Billault. Analytical contribution of NAD 2D-NMR spectroscopy in polypeptide mesophases to the investigation of triglycerides. Magnetic Resonance in Chemistry, 2012, 50, pp.S2-S11. ⟨10.1002/mrc.3855⟩. ⟨hal-02311508⟩

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Zeinab Serhan, Andrea Borgogno, Isabelle Billault, Alberta Ferrarini, Philippe Lesot. Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches. Chemistry – A European Journal, 2012, 18 (1), pp.117-126. ⟨10.1002/chem.201102775⟩. ⟨hal-02143143⟩

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Zeinab Serhan, Andrea Borgogno, Isabelle Billault, Alberta Ferrarini, Philippe Lesot. Inside Cover: Analysis of NAD 2D-NMR Spectra of Saturated Fatty Acids in Polypeptide Aligning Media by Experimental and Modeling Approaches (Chem. Eur. J. 1/2012). Chemistry – A European Journal, 2012, 18 (1), pp.2-2. ⟨10.1002/chem.201190273⟩. ⟨hal-02316063⟩

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2011

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Christie Aroulanda, Herbert Zimmermann, Zeev Luz, Philippe Lesot. Enantiotopic discrimination in the deuterium NMR spectrum of solutes with S4 symmetry in chiral liquid crystals. The Journal of Chemical Physics, 2011, 134 (13), pp.134502. ⟨10.1063/1.3554640⟩. ⟨hal-02311037⟩

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Olivier Lafon, Bingwen Hu, Jean-Paul Amoureux, Philippe Lesot. Fast and High-Resolution Stereochemical Analysis by Nonuniform Sampling and Covariance Processing of Anisotropic Natural Abundance 2D 2H NMR Datasets. Chemistry – A European Journal, 2011, 17 (24), pp.6716-6724. ⟨10.1002/chem.201100461⟩. ⟨hal-02311041⟩

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Philippe Lesot, Zeinab Serhan, Isabelle Billault. Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance 2H NMR spectroscopy: application to conjugated linolenic methyl esters. Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩. ⟨hal-02311033⟩

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Philippe Lesot, Zeinab Serhan, Isabelle Billault. Recent advances in the analysis of the site-specific isotopic fractionation of metabolites such as fatty acids using anisotropic natural-abundance H-2 NMR spectroscopy: application to conjugated linolenic methyl esters. Analytical and Bioanalytical Chemistry, 2011, 399 (3), pp.1187-1200. ⟨10.1007/s00216-010-4394-0⟩. ⟨hal-02143481⟩

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Philippe Lesot, U. Venkateswara Reddy, N. Suryaprakash. Exploring the spectral enantiodiscrimination potential of a DNA-based orienting medium using deuterium NMR spectroscopy. Chemical Communications, 2011, 47 (42), pp.11736. ⟨10.1039/C1CC15097A⟩. ⟨hal-02311046⟩

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Philippe Lesot, Christie Aroulanda, Philippe Berdagué, Herbert Zimmermann, Zeev Luz. Conformation and Dynamics of 18-Membered Hexathiametacyclophanes: A Two Step Racemization as Studied by Deuterium NMR in Chiral Lyotropic Liquid Crystals. Journal of Physical Chemistry B, 2011, 115 (41), pp.11793-11804. ⟨10.1021/jp205958k⟩. ⟨hal-02311044⟩

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2010

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Grégory Chaume, Olivier Barbeau, Philippe Lesot, Thierry Brigaud. Synthesis of 2-Trifluoromethyl-1,3-oxazolidines as Hydrolytically Stable Pseudoprolines. Journal of Organic Chemistry, 2010, 75 (12), pp.4135-4145. ⟨10.1021/jo100518t⟩. ⟨hal-02310997⟩

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J. Courtieu, C. Aroulanda, Philippe Lesot, A. Meddour, D. Merlet. Evolution of the Saupe order parameters of enantiomers from a racemic to a non-racemic liquid crystal solvent: an original light on the absolute configuration determination problem. Liquid Crystals, 2010, 37 (6-7), pp.903-912. ⟨10.1080/02678291003784164⟩. ⟨hal-02311001⟩

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Antoine Eloi, Françoise Rose-Munch, Eric Rose, Ariane Pille, Philippe Lesot, et al.. Cationic Planar Chiral (η 6 -Arene)Mn(CO) 3 + Complexes: Resolution, NMR Study in Chiral-Oriented Solvents, and Applications to the Enantioselective Synthesis of 4-Substituted Cyclohexenones and (η6 -Phosphinoarene)Mn(CO)3+ Complexes. Organometallics, 2010, 29 (17), pp.3876-3886. ⟨10.1021/om100564v⟩. ⟨hal-02316048⟩

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James Emsley, Philippe Lesot, Anne Lesage, Giuseppina de Luca, Denis Merlet, et al.. The conformation and orientational order of a 1,2-disubstituted ethane nematogenic molecule (I22) in liquid crystalline and isotropic phases studied by NMR spectroscopy. Physical Chemistry Chemical Physics, 2010, 12 (12), pp.2895. ⟨10.1039/b915587b⟩. ⟨hal-02310986⟩

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Grégory Pieters, Anne Gaucher, Sylvain Marque, François Maurel, Philippe Lesot, et al.. Regio-Defined Amino[5]Oxa- and Thiahelicenes: A Dramatic Impact of the Nature of the Heteroatom on the Helical Shape and Racemization Barriers. Journal of Organic Chemistry, 2010, 75 (6), pp.2096-2098. ⟨10.1021/jo1000127⟩. ⟨hal-04429566⟩

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Grégory Pieters, Anne Gaucher, Sylvain R A Marque, François Maurel, Philippe Lesot, et al.. Regio-defined amino[5]oxa- and thiahelicenes: A dramatic impact of the nature of the heteroatom on the helical shape and racemization barriers. Journal of Organic Chemistry, 2010, 75 (6), pp.2096-2098. ⟨10.1021/jo1000127⟩. ⟨hal-02310992⟩

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Sébastien Prevost, Sebastien Gauthier, Maria Cristina Caño de Andrade, Céline Mordant, Ali Rhida Touati, et al.. Dynamic kinetic resolution of α-chloro β-keto esters and phosphonates: hemisynthesis of Taxotere® through Ru-DIFLUORPHOS asymmetric hydrogenation. Tetrahedron: Asymmetry, 2010, 21 (11-12), pp.1436 – 1446. ⟨10.1016/j.tetasy.2010.05.017⟩. ⟨hal-01664847⟩

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Zeinab Serhan, Laura Martel, Isabelle Billault, Philippe Lesot. Complete determination of natural site-specific enantio-isotopomeric excesses in linoleic acid using natural abundance deuterium 2D NMR in polypeptide mesophases. Chemical Communications, 2010, 46 (35), pp.6599-6601. ⟨10.1039/c0cc01486a⟩. ⟨hal-02143503⟩

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2009

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Christie Aroulanda, Olivier Lafon, Philippe Lesot. Enantiodiscrimination of Flexible Cyclic Solutes Using NMR Spectroscopy in Polypeptide Chiral Mesophases: Investigation of cis -Decalin and THF. Journal of Physical Chemistry B, 2009, 113 (31), pp.10628-10640. ⟨10.1021/jp902233m⟩. ⟨hal-02310982⟩

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Vincent Baillif, Richard J. Robins, Steven Le Feunteun, Philippe Lesot, Isabelle Billault. Investigation of Fatty Acid Elongation and Desaturation Steps in Fusarium lateritium by Quantitative Two-dimensional Deuterium NMR Spectroscopy in Chiral Oriented Media. Journal of Biological Chemistry, 2009, 284 (16), pp.10783-10792. ⟨10.1074/jbc.M807826200⟩. ⟨hal-02143940⟩

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Philippe Lesot, Christie Aroulanda, Zeev Luz. Analysis of enantiotopic discrimination in the NMR spectra of prochiral solutes in chiral liquid crystals by symmetry factorization of the Saupe ordering matrix. The Journal of Chemical Physics, 2009, 131 (10), pp.104501. ⟨10.1063/1.3197853⟩. ⟨hal-02310983⟩

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Philippe Lesot, Jacques Courtieu. Natural abundance deuterium NMR spectroscopy: Developments and analytical applications in liquids, liquid crystals and solid phases. Progress in Nuclear Magnetic Resonance Spectroscopy, 2009, 55 (2), pp.128-159. ⟨10.1016/j.pnmrs.2009.01.001⟩. ⟨hal-02310981⟩

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2008

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James Emsley, Philippe Lesot, Giuseppina de Luca, Anne Lesage, Denis Merlet, et al.. A comparison of proton‐detected 13 C local field experiments with deuterium NMR at natural abundance for studying liquid crystals. Liquid Crystals, 2008, 35 (4), pp.443 – 464. ⟨10.1080/02678290801935887⟩. ⟨hal-01889736⟩

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Chun-An Fan, Benoit Ferber, Henri Kagan, Olivier Lafon, Philippe Lesot. Two aspects of the desymmetrization of selected prochiral aromatic or vinylic dihalides: enantioselective halogen–lithium exchange and prochiral recognition in chiral liquid crystals. Tetrahedron: Asymmetry, 2008, 19 (23), pp.2666-2677. ⟨10.1016/j.tetasy.2008.12.003⟩. ⟨hal-02310976⟩

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Philippe Lesot, Olivier Lafon, Christie Aroulanda, Ronald Y. Dong. 2H NMR Studies on Two-Homopolypeptide Lyotropic Enantiodiscriminating Mesophases: Experimental Quantification of Solute-Fiber Affinities. Chemistry – A European Journal, 2008, 14 (13), pp.4082-4092. ⟨10.1002/chem.200701543⟩. ⟨hal-00298353⟩

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Philippe Lesot, Olivier Lafon, Herbert Zimmermann, Zeev Luz. Enantiodiscrimination in Deuterium NMR Spectra of Flexible Chiral Molecules with Average Axial Symmetry Dissolved in Chiral Liquid Crystals: The Case of Tridioxyethylenetriphenylene. Journal of the American Chemical Society, 2008, 130 (27), pp.8754-8761. ⟨10.1021/ja800957a⟩. ⟨hal-02310973⟩

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Philippe Lesot, Olivier Lafon. Enantiomeric analysis using natural abundance deuterium 3D NMR spectroscopy in polypeptide chiral oriented media. Chemical Physics Letters, 2008, 458 (1-3), pp.219-222. ⟨10.1016/j.cplett.2008.04.065⟩. ⟨hal-02310970⟩

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Philippe Lesot, Vincent Baillif, Isabelle Billault. Combined analysis of C-18 unsaturated fatty acids using natural abundance deuterium 2D NMR spectroscopy in chiral oriented solvents. Analytical Chemistry, 2008, 80 (8), pp.2963-2972. ⟨10.1021/ac702443b⟩. ⟨hal-02143963⟩

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Philippe Lesot. RMN du deutérium en abondance naturelle dans les cristaux liquides chiraux : évolutions technologiques, avancées méthodologiques et nouvelles applications analytiques. Spectra Analyse, 2008, 262, pp.16-22. ⟨hal-02317421⟩

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2007

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Karim Ben Ali, Olivier Lafon, Herbert Zimmermann, Eric Guittet, Philippe Lesot. Homo- and heteronuclear 2D NMR approaches to analyse a mixture of deuterated unlike/like stereoisomers using weakly ordering chiral liquid crystals. Journal of Magnetic Resonance, 2007, 187 (2), pp.205-215. ⟨10.1016/j.jmr.2007.04.007⟩. ⟨hal-02310947⟩

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M. Georgy, P. Lesot, J. M. Campagne. Synthetic studies on macrolactin A : construction of C4-C24 fragment. Journal of Organic Chemistry, 2007, 72 (9), pp.3543-3549. ⟨10.1021/jo0701942⟩. ⟨hal-00166703⟩

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Olivier Lafon, Philippe Lesot, Chun-An Fan, Henri b. Kagan. Analysis of Intramolecular Dynamic Processes in Enantiomeric Diaryl Atropisomers and Related Derivatives by 2H NMR Spectroscopy in Polypeptide Liquid Crystals. Chemistry – A European Journal, 2007, 13 (13), pp.3772-3786. ⟨10.1002/chem.200601284⟩. ⟨hal-02310936⟩

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Olivier Lafon, Philippe Lesot, Herbert Zimmermann, Raphy Poupko, Zeev Luz. Chiral Discrimination in the 13 C and 2 H NMR of the Crown and Saddle Isomers of Nonamethoxy-Cyclotriveratrylene in Chiral Liquid-Crystalline Solutions. Journal of Physical Chemistry B, 2007, 111 (32), pp.9453-9467. ⟨10.1021/jp070564q⟩. ⟨hal-02310954⟩

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Jean-François Lemonnier, Sébastien Floquet, Jérôme Marrot, Emmanuel Terazzi, Claude Piguet, et al.. Structure, Formation, and Dynamics of Mo12 and Mo16 Oxothiomolybdenum Rings Containing Terephtalate Derivatives. Chemistry – A European Journal, 2007, 13 (12), pp.3548-3557. ⟨10.1002/chem.200601369⟩. ⟨hal-02310922⟩

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Latifa Ziani, Philippe Lesot, Abdelkhrim Meddour, Jacques Courtieu. Empirical determination of the absolute configuration of small chiral molecules using natural abundance 2H NMR in chiral liquid crystals. Chemical Communications, 2007, 45, pp.4737. ⟨10.1039/b711493a⟩. ⟨hal-02310959⟩

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2006

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V. Baillif, R. J. Robins, I. Billault, P. Lesot. Assignment of absolute configuration of natural abundance deuterium signals associated with (R)- and (S)-enantioisotopomers in a fatty acid aligned in a chiral liquid crystal: Enantioselective synthesis and NMR analysis. Journal of the American Chemical Society, 2006, 128, pp.11180-11187. ⟨hal-00320891⟩

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Vincent Baillif, Richard Robins, Isabelle Billault, Philippe Lesot. Assignment of Absolute Configuration of Natural Abundance Deuterium Signals Associated with ( R )- and ( S )-Enantioisotopomers in a Fatty Acid Aligned in a Chiral Liquid Crystal: Enantioselective Synthesis and NMR Analysis. Journal of the American Chemical Society, 2006, 128 (34), pp.11180-11187. ⟨10.1021/ja0617892⟩. ⟨hal-02310912⟩

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Philippe Lesot, Olivier Lafon, Henri Kagan, Chun-An Fan. Study of molecular rotational isomerism using deuterium NMR in chiral oriented solvents. Chemical Communications, 2006, 4, pp.389-391. ⟨10.1039/b514694a⟩. ⟨hal-02310907⟩

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V.L. Manthati, A.S.K. Murthy, F. Caijo, D. Drouin, P. Lesot, et al.. Enantioselective Synthesis of methyl-5-(R)-fluorohep-6-ynoate. Tetrahedron: Asymmetry, 2006, 17, pp.2306-2310. ⟨hal-00322830⟩

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Vijaya Lingam Manthati, A. Sai Krishna Murthy, Frédéric Caijo, Delphine Drouin, Philippe Lesot, et al.. Enantioselective synthesis of methyl-5(R)-fluorohept-6-ynoate. Tetrahedron: Asymmetry, 2006, 17 (15), pp.2306-2310. ⟨10.1016/j.tetasy.2006.08.010⟩. ⟨hal-02310918⟩

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2005

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Olivier Lafon, Philippe Lesot, Françoise Rose-Munch, Eric Rose, Murielle Chavarot-Kerlidou. Enantiomeric Analysis of Planar Chiral (η 6 -Arene)chromium Tricarbonyl Complexes using NMR in Oriented Solvents. Organometallics, 2005, 24 (16), pp.4021-4028. ⟨10.1021/om050239u⟩. ⟨hal-02310905⟩

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Olivier Lafon, Philippe Lesot. Deuterium 3D NMR experiments for analysing weakly aligned, isotopically enriched solutes. Chemical Physics Letters, 2005, 404 (1-3), pp.90-94. ⟨10.1016/j.cplett.2005.01.040⟩. ⟨hal-02310889⟩

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Olivier Lafon, Philippe Lesot. Theoretical and experimental investigation of 13C relayed 2H–2H-COSY 2D experiments: Application to the analysis of weakly aligned solutes. Journal of Magnetic Resonance, 2005, 174 (2), pp.254-264. ⟨10.1016/j.jmr.2005.02.011⟩. ⟨hal-02310894⟩

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Philippe Lesot. Développement et Applications de la RMN du Deutérium en Abondance naturelle dans les Cristaux Liquides Chiraux : Une autre Approche de l’Analyse en Chimie Organique. Spectra Analyse, 2005, 242, pp.37-42. ⟨hal-02317383⟩

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2004

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Krystyna Baczko, Chantal Larpent, Philippe Lesot. New amino acid-based anionic surfactants and their use as enantiodiscriminating lyotropic liquid crystalline NMR solvents. Tetrahedron: Asymmetry, 2004, 15 (6), pp.971-982. ⟨10.1016/j.tetasy.2004.01.022⟩. ⟨hal-02310787⟩

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James W. Emsley, Philippe Lesot, Jacques Courtieu, Denis Merlet. The effect of a chiral nematic solvent on the orientational order and conformational distribution of a flexible prochiral solute. Physical Chemistry Chemical Physics, 2004, 6 (23), pp.5331. ⟨10.1039/b411203b⟩. ⟨hal-02310857⟩

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James Emsley, Philippe Lesot, Denis Merlet. The orientational order and conformational distributions of the two enantiomers in a racemic mixture of a chiral, flexible molecule dissolved in a chiral nematic liquid crystalline solvent. Physical Chemistry Chemical Physics, 2004, 6 (3), pp.522. ⟨10.1039/b312512b⟩. ⟨hal-02310778⟩

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Jonathan Farjon, Jean-Pierre Baltaze, Philippe Lesot, Denis Merlet, Jacques Courtieu. Heteronuclear selective refocusing 2D NMR experiments for the spectral analysis of enantiomers in chiral oriented solvents. Magnetic Resonance in Chemistry, 2004, 42 (7), pp.594-599. ⟨10.1002/mrc.1399⟩. ⟨hal-03008490⟩

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Olivier Lafon, Denis Merlet, Jacques Courtieu, Philippe Lesot. Modified z-gradient filtering as a mean to obtain phased deuterium autocorrelation 2D NMR spectra in oriented solvents. Journal of Magnetic Resonance, 2004, 171 (1), pp.135-142. ⟨10.1016/j.jmr.2004.08.010⟩. ⟨hal-02310847⟩

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Philippe Lesot, Christie Aroulanda, Isabelle Billault. Exploring the Analytical Potential of NMR Spectroscopy in Chiral Anisotropic Media for the Study of the Natural Abundance Deuterium Distribution in Organic Molecules. Analytical Chemistry, 2004, 76 (10), pp.2827-2835. ⟨10.1021/ac030385e⟩. ⟨hal-03008466⟩

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Philippe Lesot, Olivier Lafon, Jacques Courtieu, Philippe Berdagué. Analysis of the13C NMR Spectra of Molecules, Chiral by Isotopic Substitution, Dissolved in a Chiral Oriented Environment: Towards the Absolute Assignment of the pro-R/pro-S Character of Enantiotopic Ligands in Prochiral Molecules. Chemistry – A European Journal, 2004, 10 (15), pp.3741-3746. ⟨10.1002/chem.200400065⟩. ⟨hal-02310803⟩

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2003

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Christie Aroulanda, Denis Merlet, Jacques Courtieu, Philippe Lesot. Structural Ambiguities Revisited in Two Bridged Ring Systems Exhibiting Enantiotopic Elements, Using Natural Abundance Deuterium NMR in Chiral Liquid Crystals. Journal of Physical Chemistry A, 2003, 107 (50), pp.10911-10918. ⟨10.1021/jp030137m⟩. ⟨hal-02310640⟩

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Philippe Lesot, Muriel Sarfati, Jacques Courtieu. Natural Abundance Deuterium NMR Spectroscopy in Polypeptide Liquid Crystals as a New and Incisive Means for the Enantiodifferentiation of Chiral Hydrocarbons. Chemistry – A European Journal, 2003, 9 (8), pp.1724-1745. ⟨10.1002/chem.200390199⟩. ⟨hal-05178542⟩

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Philippe Lesot, Muriel Sarfati, Denis Merlet, Bernard Ancian, James Emsley, et al.. 2D-NMR Strategy Dedicated to the Analysis of Weakly Ordered, Fully Deuterated Enantiomers in Chiral Liquid Crystals. Journal of the American Chemical Society, 2003, 125 (25), pp.7689-7695. ⟨10.1021/ja021277x⟩. ⟨hal-02310635⟩

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Michael Rivard, F. Guillen, Jean-Claude Fiaud, Christie Aroulanda, Philippe Lesot. Efficient enantiodiscrimination of chiral monophosphine oxides and boranes by phosphorus coupled 13C NMR spectroscopy in the presence of chiral ordering agents. Tetrahedron: Asymmetry, 2003, 14 (9), pp.1141-1152. ⟨10.1016/S0957-4166(03)00202-7⟩. ⟨hal-02310631⟩

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Michaël Rivard, F. Guillen, Jean-Claude Fiaud, Christie Aroulanda, Philippe Lesot. Efficient enantiodiscrimination of chiral monophosphine oxides and boranes by phosphorus coupled 13C NMR spectroscopy in the presence of chiral ordering agents. Tetrahedron: Asymmetry, 2003, 14 (9), pp.1141. ⟨10.1016/S0957-4166(03)00202-7⟩. ⟨hal-01146992⟩

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Michaël Rivard, Frédéric Guillen, Jean-Claude Fiaud, Christie Aroulanda, Philippe Lesot. Efficient enantiodiscrimination of chiral monophosphine oxides and boranes by phosphorus coupled 13C NMR spectroscopy in the presence of chiral ordering agents. Tetrahedron: Asymmetry, 2003, 14, pp.1141 – 1152. ⟨10.1016/s0957-4166(03)00202-7⟩. ⟨hal-04013355⟩

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2002

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Jonathan Farjon, Denis Merlet, Philippe Lesot, Jacques Courtieu. Enantiomeric excess measurements in weakly oriented chiral liquid crystal solvents through 2D 1H selective refocusing experiments. Journal of Magnetic Resonance, 2002, 158 (1-2), pp.169-172. ⟨10.1016/S1090-7807(02)00070-8⟩. ⟨hal-02310612⟩

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Philippe Lesot, Denis Merlet, Muriel Sarfati, Jacques Courtieu, Herbert Zimmermann, et al.. Enantiomeric and Enantiotopic Analysis of Cone-Shaped Compounds with C 3 and C 3 v Symmetry Using NMR Spectroscopy in Chiral Anisotropic Solvents. Journal of the American Chemical Society, 2002, 124 (34), pp.10071-10082. ⟨10.1021/ja020269d⟩. ⟨hal-02310599⟩

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Philippe Lesot. Résonance Magnétique Nucléaire du Deutérium en Abondance Naturelle dans les Cristaux Liquide Chiraux: Franchir une Nouvelle Frontière dans l’Analyse de la Chiralité. Lettre du Département des Sciences Chimiques du CNRS, 2002, 78, pp.13-17. ⟨hal-02321165⟩

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Arnaud Parenty, Jean-Marc Campagne, Christie Aroulanda, Philippe Lesot. Routine Use of Natural Abundance Deuterium NMR in a Polypeptidic Chiral Oriented Solvent for the Determination of the Enantiomeric Composition of Chiral Building Blocks. Organic Letters, 2002, 4 (10), pp.1663-1666. ⟨10.1021/ol020038b⟩. ⟨hal-00165644⟩

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Hélène Villar, François Guibé, Christie Aroulanda, Philippe Lesot. Investigation of SmI2-mediated cyclisation of δ-iodo-α,β-unsaturated esters by deuterium 2D NMR in oriented solvents. Tetrahedron: Asymmetry, 2002, 13 (14), pp.1465-1475. ⟨10.1016/S0957-4166(02)00259-8⟩. ⟨hal-02310609⟩

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2001

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Christie Aroulanda, Denis Merlet, Jacques Courtieu, Philippe Lesot. NMR Experimental Evidence of the Differentiation of Enantiotopic Directions in Cs and C2v Molecules Using Partially Oriented, Chiral Media. Journal of the American Chemical Society, 2001, 123 (48), pp.12059-12066. ⟨10.1021/ja011685l⟩. ⟨hal-02309135⟩

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Philippe Lesot, Muriel Sarfati, Denis Merlet, Jacques Courtieu, Bernard Ancian, et al.. Determining Enantiomeric Purity by NMR: Deuterium 2D NMR at Natural Abundance in Weakly Oriented Chiral Liquid Crystals. Bruker Report, 2001, 149, pp.29-33. ⟨hal-02321012⟩

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Muriel Sarfati, Jacques Courtieu, Philippe Lesot. First successful enantiomeric discrimination of chiral alkanes using NMR spectroscopy. Chemical Communications, 2001, 13, pp.1113-1114. ⟨10.1039/b002806l⟩. ⟨hal-02309085⟩

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Muriel Sarfati, Christie Aroulanda, Jacques Courtieu, Philippe Lesot. Enantiomeric recognition of chiral invertomers through NMR in chiral oriented phases: a study of cis-decalin. Tetrahedron: Asymmetry, 2001, 12 (5), pp.737-744. ⟨10.1016/S0957-4166(01)00103-3⟩. ⟨hal-02309129⟩

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Muriel Sarfati, Christie Aroulanda, Jacques Courtieu, Philippe Lesot. Enantiomeric recognition of chiral invertomers through NMR in chiral oriented phases: a study of cis-decalin. Tetrahedron: Asymmetry, 2001, 12 (5), pp.737-744. ⟨10.1016/S0957-4166(01)00103-3⟩. ⟨hal-02338088⟩

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2000

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Cécile Canlet, Denis Merlet, Philippe Lesot, Abdelkrim Meddour, Jacques Courtieu. Deuterium NMR stereochemical analysis of threo–erythro isomers bearing remote stereogenic centres in racemic and non-racemic liquid crystalline solvents. Tetrahedron: Asymmetry, 2000, 11 (9), pp.1911-1918. ⟨10.1016/S0957-4166(00)00125-7⟩. ⟨hal-02309123⟩

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Valérie Madiot, Philippe Lesot, Danielle Gree, Jacques Courtieu, René Grée. Highly enantioselective propargylic monofluorination established by carbon-13 and fluorine-19 NMR in chiral liquid crystals. Chemical Communications, 2000, 2, pp.169-170. ⟨10.1039/A909012F⟩. ⟨hal-02309109⟩

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Denis Merlet, Muriel Sarfati, Bernard Ancian, Jacques Courtieu, Philippe Lesot. Description of natural abundance deuterium 2D-NMR experiments in weakly ordered liquid-crystalline solvents using a tailored cartesian spin-operator formalism. Physical Chemistry Chemical Physics, 2000, 2 (10), pp.2283-2290. ⟨10.1039/b000834f⟩. ⟨hal-02309116⟩

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Muriel Sarfati, Philippe Lesot, Denis Merlet, Jacques Courtieu. Theoretical and experimental aspects of enantiomeric differentiation using natural abundance multinuclear nmr spectroscopy in chiral polypeptide liquid crystals. Chemical Communications, 2000, 21, pp.2069-2081. ⟨10.1039/B006244H⟩. ⟨hal-02309126⟩

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1999

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Olivier Dirat, Cyrille Kouklovsky, Yves Langlois, Philippe Lesot, Jacques Courtieu. Double diastereoselection in asymmetric [2+3] cycloaddition of chiral oxazoline N-oxides: application to the kinetic resolution of a racemic α,β-unsaturated δ-lactone. Tetrahedron: Asymmetry, 1999, 10 (16), pp.3197-3207. ⟨10.1016/S0957-4166(99)00317-1⟩. ⟨hal-02309107⟩

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Denis Merlet, Bernard Ancian, Jacques Courtieu, Philippe Lesot. Two-Dimensional Deuterium NMR Spectroscopy of Chiral Molecules Oriented in a Polypeptide Liquid Crystal: Applications for the Enantiomeric Analysis through Natural Abundance Deuterium NMR. Journal of the American Chemical Society, 1999, 121 (22), pp.5249-5258. ⟨10.1021/ja9837699⟩. ⟨hal-02309106⟩

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Denis Merlet, James Emsley, Philippe Lesot, Jacques Courtieu. The relationship between molecular symmetry and second-rank orientational order parameters for molecules in chiral liquid crystalline solvents. The Journal of Chemical Physics, 1999, 111 (15), pp.6890-6896. ⟨10.1063/1.479982⟩. ⟨hal-02309108⟩

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Angélique Sour, Marie-Laure Boillot, Eric Rivière, Philippe Lesot. First Evidence of a Photoinduced Spin Change in an Fe^III Complex Using Visible Light at Room Temperature. European Journal of Inorganic Chemistry, 1999, 1999 (12), pp.2117-2119. ⟨hal-05178675⟩

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1998

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Philippe Lesot, James Emsley, Jean-Michel Ouvrard, Eirian Curzon. Simplification of19F NMR Spectra of Liquid Crystalline Samples by Multiple-Pulse COSY Experiments. Journal of Magnetic Resonance, 1998, 133 (1), pp.166-172. ⟨10.1006/jmre.1998.1452⟩. ⟨hal-02309101⟩

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Philippe Lesot, Séverin Chapuis, Jean Pierre Bayle, Jacques Rault, Eric Lafontaine, et al.. Structural–dynamical relationship in silica PEG hybrid gels. Journal of Materials Chemistry, 1998, 8 (1), pp.147-151. ⟨10.1039/A704983H⟩. ⟨hal-02309086⟩

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Philippe Lesot, J. Emsley, Jacques Courtieu. The magnetohydrodynamics of a chiral nematic liquid crystal: the existence of two critical speeds revealed by deuterium NMR. Liquid Crystals, 1998, 25 (1), pp.123-127. ⟨10.1080/026782998206579⟩. ⟨hal-05178803⟩

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Philippe Lesot, Denis Merlet, Aharon Loewenstein, Jacques Courtieu. Enantiomeric visualization using proton-decoupled natural abundance deuterium NMR in poly(γ-benzyl-l-glutamate) liquid crystalline solutions. Tetrahedron: Asymmetry, 1998, 9 (11), pp.1871-1881. ⟨10.1016/S0957-4166(98)00179-7⟩. ⟨hal-02309102⟩

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Denis Merlet, Bernard Ancian, William Smadja, Jacques Courtieu, Philippe Lesot. Analysis of natural abundance deuterium NMR spectra of enantiomers in chiral liquid crystals via 2D auto-correlation experiments. Chemical Communications, 1998, 21, pp.2301-2302. ⟨10.1039/A805020A⟩. ⟨hal-02309103⟩

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D. Merlet, A. Loewenstein, W. Smadja, J. Courtieu, Philippe Lesot. Quantitative Description of the Facial Discrimination of Molecules Containing a Prochiral Group by NMR in a Chiral Liquid Crystal. Journal of the American Chemical Society, 1998, 120 (5), pp.963-969. ⟨10.1021/ja9726466⟩. ⟨hal-02309088⟩

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V. Rayssac, P. Lesot, J.-P. Bayle, S. Miyajima. Unusual ordering of a dioxyethylene chain in dialkoxy laterally substituted nematogen as evidenced by 13 C NMR. Journal de Chimie Physique et de Physico-Chimie Biologique, 1998, 95 (5), pp.973-986. ⟨10.1051/jcp:1998225⟩. ⟨hal-02309089⟩

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1997

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Philippe Lesot, Denis Merlet, Jacques Courtieu, James Emsley, Tapio Rantala, et al.. Calculation of the Molecular Ordering Parameters of (±)-3-Butyn-2-ol Dissolved in an Organic Solution of Poly(γ-benzyl- l -glutamate). Journal of Physical Chemistry A, 1997, 101 (31), pp.5719-5724. ⟨10.1021/jp9709262⟩. ⟨hal-02309087⟩

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Philippe Lesot, Felix Perez, Patrick Judeinstein, Jean Pierre Bayle, Hassan Allouchi, et al.. Steric Hindrance Influence of a Diazo Link upon Mesogenic Properties of some Ligands and Related Copper Complexes. Journal de Chimie Physique, 1997, 94, pp.1695-1714. ⟨hal-02320964⟩

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A. Meddour, P. Berdague, A. Hedli, J. Courtieu, Philippe Lesot. Proton-decoupled carbon-13 NMR spectroscopy in a lyotropic chiral nematic solvent as an analytical tool for the measurement of the enantiomeric excess. Journal of the American Chemical Society, 1997, 119 (19), pp.4502-4508. ⟨10.1021/ja964002o⟩. ⟨hal-02324618⟩

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1996

ref_biblio

Philippe Lesot, Denis Merlet, Jacques Courtieu, J. Emsley. Discrimination and analysis of the NMR spectra of enantiomers dissolved in chiral liquid crystal solvents through 2D correlation experiments. Liquid Crystals, 1996, 21 (3), pp.427-435. ⟨10.1080/02678299608032851⟩. ⟨hal-02308703⟩

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1995

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Philippe Lesot, Yves Gounelle, Denis Merlet, Aharon Loewenstein, Jacques Courtieu. Measurement and Analysis of the Molecular Ordering Tensors of Two Enantiomers Oriented in a Polypeptide Liquid Crystalline System. The Journal of physical chemistry, 1995, 99 (40), pp.14871-14875. ⟨10.1021/j100040a042⟩. ⟨hal-02309083⟩

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Philippe Lesot, Denis Merlet, Abdelkrim Meddour, Jacques Courtieu, Aharon Loewenstein. Visualization of enantiomers in a polypeptide liquid-crystal solvent through carbon-13 NMR spectroscopy. Journal of the Chemical Society, Faraday Transactions, 1995, 91 (9), pp.1371. ⟨10.1039/ft9959101371⟩. ⟨hal-02309082⟩

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1994

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Philippe Lesot, J.M. Ouvrard, B.N. Ouvrard, J. Courtieu. Coherent Reduction of Dipolar Interactions in Molecules Dissolved in Anisotropic Media Using a New Multiple-Pulse Sequence in a COSY Experiment. Journal of magnetic resonance. Series A, 1994, 107 (2), pp.141-150. ⟨10.1006/jmra.1994.1061⟩. ⟨hal-02309080⟩

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Philippe Lesot, F. Nielsen, J. Ouvrard, J. Courtieu. Multiple-pulse COSY NMR spectroscopy of oriented molecules in thermotropic cholesteric. The Journal of physical chemistry, 1994, 98 (49), pp.12849-12855. ⟨10.1021/j100100a009⟩. ⟨hal-02309081⟩

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Conference papers

2024

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Bernard Rousseau, Ambre Courteaud, Philippe Lesot. Prediction of Anisotropic NMR Parameters in a PBLG based Chiral Liquid Crystal A comparison between Experiments and Molecular Dynamics Simulations. CHIRAFUN, GdR Chirafun, Sep 2024, Orsay, France. ⟨hal-04928867⟩

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2019

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Olivier Lafon, Julien Trebosc, Eriks Kupče, Philippe Lesot, Jean-Paul Amoureux. Acquisition rapide de spectres RMN multidimensionnels de solides en utilisant des échantillonnages alternatifs. Groupement d’Etudes de Résonance Magnétique (GERM), May 2019, Saint Pierre d’Oléron, France. ⟨hal-04438434⟩

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2016

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Philippe Berdagué, Jérémy Jacob, Valery J. Terwilliger, Claude Le Milbeau, Philippe Lesot. Conditions environnementales, biosynthèses, diagenèse : contribution analytique de la RMN 2H en milieu anisotrope. 4èmes Journées Climat et Impacts, Nov 2016, Orsay, France. ⟨hal-01689725⟩

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Philippe Lesot, Philippe Berdagué, Jérémy Jacob. (D/H) Isotopic Fractionation by Anisotropic NAD 2D-NMR Spectroscopy: Exploiting the Analytical Wealth of Oriented Solvents to Investigate Molecules of Interest. 8th International Symposium on Isotopomers, Oct 2016, Nantes, France. ⟨hal-01401863⟩

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2015

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Philippe Berdagué, Jérémy Jacob, Valerie Terwilliger, Claude Lemilbeau, Philippe Lesot. Contribution de la RMN 2D DAN anisotrope à la détermination du profil isotopique (D/H) i dans des biomarqueurs: étude de la miliacine. Colloque RMN GBP-Ile de France, May 2015, Gif-sur-Yvette, France. ⟨hal-01400951⟩

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Jérémy Jacob, Anaëlle Simonneau, Nicolas Bossard, Claude Le Milbeau, Marlène Lavrieux, et al.. Miliacin from broomcorn millet – a fossil molecule of multiple interests for archaeologists and paleoenvironmentalists. Millet Cultivation in the Caucasus from the 6th to the 2nd mill BC: Origin and Development, Nov 2015, Lyon, France. ⟨hal-01400923⟩

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Lucie Vandromme, Li Chen, Lai Wei, Franck Le Bideau, André Loupy, et al.. Chiral imines on the wave: reactivity of tert-butyl acrylate and stereoselectivity determination using NMR in liquid crystals. MOL2NET, International Conference on Multidisciplinary Sciences, 2015, SCIForum, France. pp.1-18, ⟨10.3390/MOL2NET-1-a003⟩. ⟨hal-02314359⟩

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2013

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Philippe Berdagué, Philippe Lesot, Jérémy Jacob, Valery T. Terwilliger, Claude Le Milbeau. Hydrogen Isotope Profile of Methyl Groups in Miliacin (olean-18-en-3βol ME) by Natural Abundance Deuterium 2D-NMR Spectroscopy in liquid crystals. the 26th International Meeting on Organic Geochemistry (IMOG 2013), Sep 2013, Tenerife, Spain. 3p. ⟨insu-00843521⟩

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2012

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Grégory Chaume, Olivier Barbeau, Philippe Lesot, Emeric Miclet, Thierry Brigaud. Methodological Study of the Peptide Coupling of the N-desactivated Stable Proline Surrogate CF3-pseudoproline. 32nd European Peptide Symposium, 2012, Sitges, France. pp.S58-S200, ⟨10.1002/psc.2449⟩. ⟨hal-02316083⟩

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Book sections

2023

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Philippe Lesot, Roberto R. Gil. Anisotropic 1D/2D NMR in Molecular Analysis. K. Ivanov; P.K. Madhu; G. Rajalakshmi. Two-Dimensional (2D) NMR Methods, Wiley, pp.209-296, 2023, ⟨10.1002/9781119806721.ch9⟩. ⟨hal-04218745⟩

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Philippe Lesot, Olivier Lafon. Combining Fast 2D NMR Methods and Oriented Media. Jean-Nicolas Dumez; Patrick Giraudeau. Fast 2D Solution-state NMR: Concepts and Applications, 1, The Royal Society of Chemistry, 2023, 978-1-83916-400-2. ⟨10.1039/BK9781839168062-00441⟩. ⟨hal-04207389⟩

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Philippe Lesot, Gérald Remaud, Ben-Li Zhang. Specific Natural Isotope Fractionation Studied by 2H Nuclear Magnetic Resonance (SNIF-NMR): History, Developments, and Applications. Handbook of Isotopologue Biogeochemistry, Springer Nature Singapore, pp.1-41, 2023, ⟨10.1007/978-981-10-7048-8_38-1⟩. ⟨hal-04215287⟩

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2018

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Philippe Lesot. Nuclear Magnetic Resonance Spectroscopy-Applicable Elements—Hydrogen Isotopes: 2 H NMR. Reference Module in Chemistry, Molecular Sciences and Chemical Engineering, 7, Elsevier, pp.152-167, 2018, ⟨10.1016/B978-0-12-409547-2.14084-3⟩. ⟨hal-02334009⟩

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2017

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Gérald Remaud, Patrick Giraudeau, Philippe Lesot, Serge Akoka. Isotope Ratio Monitoring by NMR. Part 1: Recent Advances. Ed. G. Webb. Modern Magnetic Resonance, 2nd Edition, 1-25, Springer International Publishing, 2017, 978-3-319-28275-6. ⟨10.1007/978-3-319-28275-6⟩. ⟨hal-02308872⟩

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Richard J. Robins, Gérald Remaud, Isabelle Billault, Philippe Lesot. Isotope Ratio Monitoring by NMR. Part 2: New Applications in the Field of Defining Biosynthesis. Ed. G. Webb. Modern Magnetic Resonance, 2nd Edition, Springer International Publishing, pp.1-26, 2017, 978-3-319-28275-6. ⟨10.1007/978-3-319-28275-6_9-1⟩. ⟨hal-02321193⟩

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2016

ref_biblio

Philippe Lesot, Olivier Lafon. Natural Abundance Deuterium NMR Spectroscopy. Encyclopedia of Spectroscopy and Spectrometry, Elsevier, pp.1-14, 2016, ⟨10.1016/B978-0-12-409547-2.12110-9⟩. ⟨hal-02308860⟩

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2014

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Chantal Andraud, Philippe Belmont, J.M. Campagne, Gaëlle Chouraqui, Emmanuel Gras, et al.. Rapport de Conjoncture du CoNRS 2014 (INC / Section 12). CNRS Editions, Paris,. Rapport de Conjoncture du CoNRS 2014, CNRS Editions, Paris,, pp.255-274, 2014, 978-2-271-08746-1. ⟨hal-02338362⟩

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2013

ref_biblio

Philippe Lesot. Deuterium NMR of Liquid-crystalline Samples at Natural Abundance. Encyclopedia of Magnetic Resonance (eMagRes, 2 (3), John Wiley & Sons, Ltd, pp.315-334, 2013, 780470034590. ⟨10.1002/9780470034590⟩. ⟨hal-02316109⟩

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2011

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Chantal Andraud, Janick Ardisson, Didier Bourissou, Elisabet Dunach, J.C. Guillemin, et al.. Architectures moléculaires : synthèses, mécanismes et propriétés. Rapport de Conjoncture du Comité national de la recherche scientifique 2010, CNRS éditions, pp.231-242, 2011, 978-2-271-07263-4. ⟨hal-02338332⟩

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2010

ref_biblio

Philippe Lesot, Christie Aroulanda. Analytical Potentials of Natural Abundance Deuterium NMR Spectroscopy In Achiral Thermotropics and Polypeptide Chiral Liquid Crystals. World Scientific Publishing Co. Pte. Ltd. NMR Spectroscopy of Liquid Crystals,, pp.37-78, 2010. ⟨hal-02317644⟩

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2007

ref_biblio

Philippe Lesot. Deuterium NMR of Liquid-crystalline Samples at Natural Abundance. EMagRes (Encyclopedia of Magnetic Resonance), 9 (37), John Wiley & Sons, Ltd, pp.1943-1948, 2007, ⟨10.1002/9780470034590.emrstm1318⟩. ⟨hal-03008886⟩

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2002

ref_biblio

Jacques Courtieu, Philippe Lesot, Denis Merlet, Abdelkrim Meddour, Christie Aroulanda. Chiral Liquid Crystal NMR: a Tool for Enantiomeric Analysis. Eds. D.M. Grant & R.K. Harris, J. Wiley & Sons. Encyclopedia of NMR: Advances in NMR », 1st print edition, 9, pp.497-505, 2002. ⟨hal-02321152⟩

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Other publications

2002

ref_biblio

Philippe Lesot. L’art de discriminer des énantiomères. 2002, pp.18-19. ⟨hal-02321156⟩

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Reports

2023

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Balan Lavinia, Marylène Bertrand, Roberta Bongiovanni, Catherine Debiemme-Chouvy, Marie-Hélène Delville, et al.. Rapport de Prospective 2023 du Conseil Scientifique de l’Institut de Chimie du CNRS (Mandature 2019-2023). Centre national de la recherche scientifique (CNRS). 2023. ⟨hal-04307872v2⟩

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