Journal articles

2026

Guillaume Schoenn, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Diversification of the Avarane Skeleton Toward Spiroetherone A. ChemistryEurope, 2026, 4 (9), pp.e70350. ⟨10.1002/ceur.70350⟩. ⟨hal-05770600⟩

Wei Cao, Alicia Ross, Jean‐pierre Baltaze, Régis Guillot, Menglin Xu, et al.. Toward the Synthesis of Pestalustaine A: Structural Revision and Formation of Original Strained Tricyclic Architectures. Angewandte Chemie International Edition, 2026, 65 (37), pp.e7194437. ⟨10.1002/anie.7194437⟩. ⟨hal-05688259⟩

Elisa Coll, Vincent Gandon, Cyrille Kouklovsky, Laurent Evanno, Guillaume Vincent. Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation. Angewandte Chemie International Edition, 2026, 17 (65), pp.e4281634. ⟨10.1002/anie.4281634⟩. ⟨hal-05589026⟩

2025

Guillaume Schoenn, Cyrille Kouklovsky, Régis Guillot, Thomas Magauer, Guillaume Vincent. Total Synthesis of Dactyloquinone A and Spiroetherone A via a Metal‐Hydride Hydrogen Atom Transfer (MHAT) Process and a Quinol–Enedione Rearrangement. Angewandte Chemie International Edition, 2025, 64 (25), pp.e202505270. ⟨10.1002/anie.202505270⟩. ⟨hal-05348489⟩

Antoine Lefevre, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Synthesis of γ-Lactones from the Intermolecular Oxidative Coupling between Malonates and Styrenes. Journal of Organic Chemistry, 2025, 90 (12), pp.4450-4457. ⟨10.1021/acs.joc.5c00228⟩. ⟨hal-05117275⟩

2024

Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, Guillaume Vincent. Total Synthesis of Mavacuran Alkaloids with Bioinspired and non-Bioinspired Strategies. SYNLETT, 2024, 35 (5), pp.521-534. ⟨10.1055/s-0042-1751498⟩. ⟨hal-04274139⟩

Antoine Lefevre, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Ferrocene-Mediated Electrochemical Polycyclization of Malonates. Organic Letters, 2024, 26 (35), pp.521-534. ⟨10.1021/acs.orglett.4c02727⟩. ⟨hal-04762091⟩

2023

Audrey Mauger, Maxime Jarret, Aurélien Tap, Rémi Perrin, Régis Guillot,, et al.. Collective Total Synthesis of Mavacuran Alkaloids via an Intermo-lecular 1,4-Addition Approach. Angewandte Chemie International Edition, 2023, 62, ⟨10.1002/anie.202302461⟩. ⟨hal-04274088⟩

Shanyu Tang, Guillaume Vincent. Benzylic C–H arylation with dicyanoarenes via convergent paired electrolysis. Green Chemistry, 2023, 25 (14), pp.5483 – 5488. ⟨10.1039/d3gc00866e⟩. ⟨hal-04274110⟩

2022

Shanyu Tang, Régis Guillot, Laurence Grimaud, Maxime Vitale, Guillaume Vincent. Electrochemical Benzylic C–H Functionalization with Isocyanides. Organic Letters, 2022, 24 (11), pp.2125-2130. ⟨10.1021/acs.orglett.2c00364⟩. ⟨hal-03787339⟩

Wei Cao, Yingchao Dou, Cyrille Kouklovsky, Guillaume Vincent. Total Synthesis of Ophiorrhine A, G and Ophiorrhiside E Featuring a Bioinspired Intramolecular Diels–Alder Cycloaddition. Angewandte Chemie International Edition, 2022, 61 (38), pp.e202209135. ⟨10.1002/anie.202209135⟩. ⟨hal-03837639⟩

Anaïs Rousseau, Guillaume Vincent, Cyrille Kouklovsky. Preparation of an advanced intermediate for the synthesis of leustroducsins and phoslactomycins by heterocycloaddition. Beilstein Journal of Organic Chemistry, 2022, 18, pp.1385-1395. ⟨10.3762/bjoc.18.143⟩. ⟨hal-03838971⟩

Nazarii Sabat, Weiping Zhou, Vincent Gandon, Xavier Guinchard, Guillaume Vincent. Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles. Angewandte Chemie International Edition, 2022, 61 (30), pp.e202204400. ⟨10.1002/anie.202204400⟩. ⟨hal-03769481⟩

2021

Maxime Jarret, Hussein Abou-Hamdan, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Bioinspired Early Divergent Oxidative Cyclizations toward Pleiocarpamine, Talbotine, and Strictamine. Organic Letters, 2021, 23 (4), pp.1355-1360. ⟨10.1021/acs.orglett.1c00018⟩. ⟨hal-03186900⟩

Anne-Sophie Marques, Isabelle Chataigner, Vincent Coeffard, Guillaume Vincent, Xavier Moreau. Des molécules polycycliques 3D à portée de dominos. L’Actualité Chimique, 2021, 459, pp.27-30. ⟨hal-03376202⟩

Shanyu Tang, Guillaume Vincent. Natural products originated from the oxidative coupling of tyrosine and tryptophan: biosynthesis and bioinspired synthesis. Chemistry – A European Journal, 2021, 27, pp.2612-2622. ⟨10.1002/chem.202003459⟩. ⟨hal-02960526⟩

Audrey Mauger, Maxime Jarret, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. The chemistry of mavacurane alkaloids: a rich source of bis-indole alkaloids. Natural Product Reports, 2021, 30 (10), pp.1852-1886. ⟨10.1039/D0NP00088D⟩. ⟨hal-03186969⟩

Hussein Abou-Hamdan, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of a Seco iso -Secologanin Aglycone Analogue of Interest toward Secoiridoids and Monoterpene Indole Alkaloids. Journal of Organic Chemistry, 2021, 86 (13), pp.9244-9252. ⟨10.1021/acs.joc.1c00916⟩. ⟨hal-03286160⟩

2020

Yingchao Dou, Cyrille Kouklovsky, Guillaume Vincent. Bioinspired Divergent Oxidative Cyclization from Strictosidine and Vincoside Derivatives: Second Generation Total Synthesis of Cymoside and Access to an Original Hexacyclic‐Fused Furo[3,2‐b]indoline. Chemistry – A European Journal, 2020, 26 (71), pp.17190-17194. ⟨10.1002/chem.202003758⟩. ⟨hal-02960522⟩

Maxime Jarret, Aurélien Tap, Victor Turpin, Natacha Denizot, Cyrille Kouklovsky, et al.. Bioinspired Divergent Oxidative Cyclizations of Geissoschizine: Total Synthesis of (–)‐17‐nor‐Excelsinidine, (+)‐16‐epi‐Pleiocarpamine, (+)‐16‐Hydroxymethyl‐Pleiocarpamine and (+)‐Taberdivarine H. European Journal of Organic Chemistry, 2020, 40, pp.6340-6351. ⟨10.1002/ejoc.202000962⟩. ⟨hal-02960543⟩

Ju Wu, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Dearomative Dihydroxylation and Hydroxycyclization of Indoles. Advanced Synthesis and Catalysis, 2020, 362 (8), pp.1712-1719. ⟨10.1002/adsc.202000158⟩. ⟨hal-02960497⟩

Ju Wu, Hussein Abou-Hamdan, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical synthesis of 3a-bromofuranoindolines and 3a-bromopyrroloindolines mediated by MgBr 2. Chemical Communications, 2020, 56 (11), pp.1713-1716. ⟨10.1039/C9CC09276E⟩. ⟨hal-02960483⟩

Yingchao Dou, Cyrille Kouklovsky, Vincent Gandon, Guillaume Vincent. Enantioselective Total Synthesis of Cymoside through a Bioinspired Oxidative Cyclization of a Strictosidine Derivative. Angewandte Chemie International Edition, 2020, 59 (4), pp.1527-1531. ⟨10.1002/anie.201912812⟩. ⟨hal-02471140⟩

Hussein Abou-Hamdan, Cyrille Kouklovsky, Guillaume Vincent. Dearomatization Reactions of Indoles to Access 3D Indoline Structures. SYNLETT, 2020, 31 (18), pp.1775-1788. ⟨10.1055/s-0040-1707152⟩. ⟨hal-02960505⟩

2019

Léo Birbaum, Laurent Gillard, Hélène Gérard, Hassan Oulyadi, Guillaume Vincent, et al.. Dearomatization of 3‐Nitroindoles with Highly γ‐Functionalized Allenoates in Formal (3+2) Cycloadditions. Chemistry – A European Journal, 2019, 25 (60), pp.13688-13693. ⟨10.1002/chem.201903455⟩. ⟨hal-02330833⟩

Maxime Jarret, Victor Turpin, Aurélien Tap, Jean-François Gallard, Cyrille Kouklovsky, et al.. Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for Enantioselective Total Synthesis of Mavacuran Alkaloids. Angewandte Chemie International Edition, 2019, 58 (29), pp.9861-9865. ⟨10.1002/anie.201905227⟩. ⟨hal-02322586⟩

Anne-Sophie Marques, Thibaut Duhail, Jérôme Marrot, Isabelle Chataigner, Vincent Coeffard, et al.. A Fused Hexacyclic Ring System: Diastereoselective Polycyclization of 2,4-Dienals through an Interrupted iso-Nazarov Reaction. Angewandte Chemie International Edition, 2019, 58 (29), pp.9969-9973. ⟨10.1002/anie.201903860⟩. ⟨hal-02322633⟩

Ju Wu, Yingchao Dou, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Dearomative 2,3-Difunctionalization of Indoles. Journal of the American Chemical Society, 2019, 141 (7), pp.2832-2837. ⟨10.1021/jacs.8b13371⟩. ⟨hal-02322510⟩

Dmytro Ryzhakov, Maxime Jarret, Jean-Pierre J.-P. Baltaze, Régis Guillot, Cyrille Kouklovsky, et al.. Synthesis of 3,3-Spirocyclic 2-Phosphonoindolines via a Dearomative Addition of Phosphonyl Radicals to Indoles. Organic Letters, 2019, 21 (13), pp.4986-4990. ⟨10.1021/acs.orglett.9b01516⟩. ⟨hal-02322542⟩

2018

Natacha Denizot, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. N-Iodosuccinimide-Mediated Oxidative Coupling of Indoles and Phenols: A Synthetic Study toward the Benzofuroindoline Moiety of Bipleiophylline. Synthesis: Journal of Synthetic Organic Chemistry, 2018, 50 (24), pp.4823-4828. ⟨10.1055/s-0036-1592002⟩. ⟨hal-02348825⟩

Natacha Denizot, David Lachkar, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Divergent Oxidative Couplings between Indoles and 2,3-Dihydroxybenzoic Acid Derivatives for the Biomimetic Synthesis of Voacalgine A and Bipleiophylline. Synthesis: Journal of Synthetic Organic Chemistry, 2018, 50 (21), pp.4229-4242. ⟨10.1055/s-0036-1591910⟩. ⟨hal-02348831⟩

Maxime Jarret, Aurélien Tap, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Total Synthesis of (−)-17-nor-Excelsinidine. Angewandte Chemie International Edition, 2018, 57 (38), pp.12294-12298. ⟨10.1002/anie.201802610⟩. ⟨hal-02348789⟩

Ju Wu, Raj Kumar Nandi, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Dearomative Diallylation of N -Acylindoles Mediated by FeCl 3. Organic Letters, 2018, 20 (7), pp.1845-1848. ⟨10.1021/acs.orglett.8b00361⟩. ⟨hal-02348801⟩

Raj Kumar Nandi, Alejandro Perez-Luna, Didier Gori, Rodolphe Beaud, Régis Guillot, et al.. Triflic Acid as an Efficient Brønsted Acid Promoter for the Umpolung of N-Ac Indoles in Hydroarylation Reactions. Advanced Synthesis and Catalysis, 2018, 360 (1), pp.161-172. ⟨10.1002/adsc.201701074⟩. ⟨hal-02348844⟩

A.-S. Marques, J. Marrot, Isabelle Chataigner, V. Coeffard, G. Vincent, et al.. In Situ Generation of Cyclopentadienol Intermediates from 2,4-Dienals. Application to the Synthesis of Spirooxindoles via a Domino Polycyclization. Organic Letters, 2018, 20 (3), pp.792-795. ⟨10.1021/acs.orglett.7b03934⟩. ⟨hal-02024515⟩

2017

Anaïs Rousseau, Marie Buchotte, Régis Guillot, Guillaume Vincent, Cyrille Kouklovsky. Expedient Approach to α,β‐Unsaturated δ‐Lactones through a Catalytic Asymmetric [2+2] Cycloaddition. European Journal of Organic Chemistry, 2017, 2017 (45), pp.6804-6810. ⟨10.1002/EJOC.201701336⟩. ⟨hal-05771017⟩

Dmytro Ryzhakov, Maxime Jarret, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Radical-Mediated Dearomatization of Indoles with Sulfinate Reagents for the Synthesis of Fluorinated Spirocyclic Indolines. Organic Letters, 2017, 19 (23), pp.6336-6339. ⟨10.1021/ACS.ORGLETT.7B03155⟩. ⟨hal-05771003⟩

David Lachkar, Natacha Denizot, Guillaume Bernadat, Kadiria Ahamada, Mehdi Beniddir, et al.. Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings. Nature Chemistry-, 2017, 9 (8), pp.793-798. ⟨10.1038/nchem.2735⟩. ⟨hal-05115363⟩

Terry Tomakinian, Hussein Abou Hamdan, Natacha Denizot, Régis Guillot,, Jean-Pierre Baltaze, et al.. Evaluation of an NIS-Mediated Oxidative Cyclisation of Phenol-Containing N-Acyltryptamine Precursors towards Phalarine: Synthesis of 4 ‘,5 ‘-Dihydrospiro[indole-3,6 ‘-[1,3]oxazine]s. European Journal of Organic Chemistry, 2017, 2017 (19), pp.2757-2763. ⟨10.1002/ejoc.201601563⟩. ⟨hal-05255498⟩

Rodolphe Beaud, Raj Kumar Nandi, Alejandro Perez-Luna, Régis Guillot, Didier Gori, et al.. Revealing the electrophilicity of N-Ac indoles with FeCl _\textrm3 : a mechanistic study. Chemical Communications, 2017, 53 (43), pp.5834–5837. ⟨10.1039/C7CC02756G⟩. ⟨hal-01712357⟩

2016

Raj Kumar Nandi, Friederike Ratsch, Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, et al.. Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl 3. Chemical Communications, 2016, 52 (30), pp.5328-5331. ⟨10.1039/C6CC01654E⟩. ⟨hal-05770958⟩

Terry Tomakinian, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of benzofuro[3,2-b]indoline amines via deamination-interrupted Fischer indolization and their unexpected reactivity towards nucleophiles. Chemical Communications, 2016, 52 (31), pp.5443-5446. ⟨10.1039/C6CC00365F⟩. ⟨hal-05770941⟩

Raj Kumar Nandi, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of 3,3-Spiroindolines via FeCl 3 -Mediated Cyclisation of Aryl or Alkene-Containing 3-Substituted N-Ac Indoles. Organic Letters, 2016, 18 (8), pp.1716-1719. ⟨10.1021/acs.orglett.6b00174⟩. ⟨hal-01509939⟩

2015

Natacha Denizot, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Connecting Tyrosine and Tryptophan Units of Diazonamide A and Azonazine by a Diastereodivergent Arylative Dearomatization. Chemistry – A European Journal, 2015, 21 (52), pp.18953-18956. ⟨10.1002/CHEM.201503612⟩. ⟨hal-05770912⟩

2014

Natacha Denizot, Annie Pouilhès, Mélissa Cucca, Rodolphe Beaud, Régis Guillot, et al.. Bioinspired Direct Access to Benzofuroindolines by Oxidative [3 + 2] Annulation of Phenols and Indoles. Organic Letters, 2014, 16 (21), pp.5752-5755. ⟨10.1021/OL502820P⟩. ⟨hal-05770847⟩

Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Regioselective Hydroarylation Reactions of C3 Electrophilic N ‐Acetylindoles Activated by FeCl 3 : An Entry to 3‐(Hetero)arylindolines. Chemistry – A European Journal, 2014, 20 (24), pp.7492-7500. ⟨10.1002/CHEM.201400284⟩. ⟨hal-05770816⟩

2012

Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. FeCl 3 ‐Mediated Friedel–Crafts Hydroarylation with Electrophilic N ‐Acetyl Indoles for the Synthesis of Benzofuroindolines. Angewandte Chemie International Edition, 2012, 51 (50), pp.12546-12550. ⟨10.1002/ANIE.201206611⟩. ⟨hal-05770716⟩

2011

Guillaume Vincent, Régis Guillot, Cyrille Kouklovsky. Stereodivergent Synthesis of Substituted N,O‐Containing Bicyclic Compounds by Sequential Addition of Nucleophiles to N ‐Alkoxybicyclolactams. Angewandte Chemie International Edition, 2011, 50 (6), pp.1350-1353. ⟨10.1002/ANIE.201006590⟩. ⟨hal-05769771⟩

Conference papers

2025

Guillaume Vincent. Oxidative Couplings and Total Synthesis of Natural Products. Colloque Transferts Electronique, Collège de France, Louis Fensterbank, May 2025, Paris, France. ⟨hal-05134248⟩

Poster communications

2024

Antoine Lefèvre, Guillaume Vincent. Toward the enantioselective synthesis of complex molecules with electrochemistry. Belgian Organic Synthesis Symposium (BOSS), Jun 2024, Liège, Belgium. ⟨hal-05118190⟩

Antoine Lefèvre, Guillaume Vincent. Toward the enantioselective synthesis of complex molecules with electrochemistry. French Industrial Chemistry Symposium (FICS), Apr 2024, Paris, France. ⟨hal-05118181⟩

Antoine Lefèvre, Guillaume Vincent. Toward the enantioselective synthesis of complex molecules with electrochemistry. Rencontres de Chimie Organique (RCO), Apr 2024, Orsay, France. ⟨hal-05118149⟩

2022

Antoine Lefèvre, Guillaume Vincent. Towards the enantioselective synthesis of complex molecules with eletrochemistry. Journées de Chimie Organique (JCO), Nov 2022, Palaiseau (Ecole Polytechnique), France. ⟨hal-05118130⟩

Shanyu Tang, Laurence Grimaud, Maxime R. Vitale, Guillaume Vincent. Electrochemical Benzylic C(sp3 )-H Functionalization for the C-C Bond Formation. Journées de Chimie Organique (JCO), Nov 2022, Palaiseau (Ecole Polytechnique), France. ⟨hal-05118106⟩

Shanyu Tang, Laurence Grimaud, Maxime R. Vitale, Guillaume Vincent. Electrochemical Benzylic C(sp3 )-H Functionalization for the C-C Bond Formation. Belgian Organic Synthesis Symposium (BOSS), Jul 2022, Namur, Belgium. ⟨hal-05118086⟩