Institut de Chimie Moléculaire
& des Matériaux d’OrsaY
ACCÈS

Notre adresse

Institut de Chimie Moléculaire et des Matériaux d’Orsay
Bâtiment 670, Université Paris-Saclay, UMR 8182
17 Avenue des Sciences
91400 Orsay – France

Pour venir à l’ICMMO

Situé sur le plateau de Saclay, l’ICMMO fait partie de la faculté des sciences d’Orsay. Vous pouvez venir à l’ICMMO en transports en commun ou en voiture. Voyez le plan du campus .

Par la route

En venant de Paris, deux possibilités :

  • Paris-Ouest : à la porte de Saint-Cloud prendre la N118, direction Chartres-Orléans, sortie 9, Centre Universitaire-Grandes Ecoles – Orsay-Le Guichet. Puis au rond-point, prendre la 2nde sortie Rue Louis de Broglie et tourner à droite sur l’Avenue des Sciences.
  • Paris-Sud : à partir de la Porte d’Orléans prendre l’autoroute A10 direction Bordeaux-Nantes, puis Chartres-Orléans, sortie Orsay-Bures. Emprunter la N118 jusqu’à la sortie 9, Centre Universitaire-Grandes Ecoles – Gif sur Yvette. Puis au rond-point, 1ère sortie Centre universitaire et au second rond-point, prendre la 3eme sortie Rue Louis de Broglie et tourner à droite sur l’Avenue des Sciences.

Pour le stationnement voir ici .

Par les transports en commun

Prendre le RER ligne B en direction de Saint-Rémy-les-Chevreuse, descendre à la station Le Guichet puis prendre le bus 4609 ou descendre à la station Orsay puis prendre le bus 4607 à Gare d’Orsay – l’Yvette.

Institut de Chimie Moléculaire et des Matériaux d Orsay
Bat 670
17 Av. des Sciences
91190 Orsay

Giang Vo-thanh

giang.vo-thanh@-Code to remove to avoid SPAM-universite-paris-saclay.fr
0169157891, room 2304
Giang Vo-Thanh received his M.Sc. degree in 1994 and his Ph.D. in Organic Chemistry in 1997 from Université Pierre et Marie Curie (Paris VI). Following three years of postdoctoral research fellowships, he joined Université Paris-Sud as an Assistant Professor in 2001, obtained his Habilitation à Diriger des Recherches (HDR) in 2006, and was promoted to Full Professor of Organic Chemistry at Université Paris-Sud (now Université Paris-Saclay) in 2007. His scientific research spans synthetic organic methodology, green chemistry, and asymmetric catalysis, with primary expertise in the design, synthesis, and application of functionalized chiral ionic liquids as novel reaction media in asymmetric transformations, the development of chiral bifunctional organocatalysts derived from bio-based or readily available feedstocks for asymmetric synthesis and biomass valorization, as well as the target-directed synthesis and stereoselective assembly of biologically active molecules and functionalized molecular scaffolds for medicinal and bio-organic applications.
Collaborations internationales :
Prof. Shu Kobayashi (School of Science, The University of Tokyo), Prof. Hiroaki Sasai (ISIR, The University of Osaka), Prof. Shinobu Takizawa (SANKEN, The University of Osaka), Prof. Ye Liu (East China Normal University, Shanghai), Prof. Vu Thi Thu Ha (Vietnam Academy of Science and Technology, VAST), Prof. Doan Thi Mai Huong (VAST).
Collaborations nationales :
Dr. Jean-François Betzer (ICSN, CNRS), Dr. Thanh-Binh Nguyen (ICSN, CNRS), Dr. Peter Hesemann (CNRS, Université de Montpellier).Dr. Jean-François Brière (CNRS, Université de Rouen).
Collaborations industrielles :
Société Roquette, Société CEM.

Journal articles

2026

Zhiwei Lu, Thi Thanh Tam Nguyen, Martial Toffano, Chloée Bournaud, Giang Vo-Thanh, et al.. Access to (E)-2-(Benzo[1,2]dithiol-3-ylidene)acetonitriles via Three Component Reaction of o-Nitro-/Halo-Benzaldehydes, Cyanoacetates and Sulfur. Organic Letters, In press, ⟨10.1021/acs.orglett.6c02848⟩. ⟨hal-05733482⟩ PDF
Zhiwei Jiang, Martial Toffano, Régis Guillot, Chloée Bournaud, Giang Vo-Thanh. N-Heterocyclic Carbene-Catalyzed Generation of Homoenolates: Efficient Asymmetric Synthesis of Dispirocyclopentanones by Direct Annulation of Enals and Isoindigos. Catalysts, 2026, 16 (2), pp.138. ⟨10.3390/catal16020138⟩. ⟨hal-05523376⟩ PDF

2024

Chloée Bournaud, Martial Toffano, Giang Vo-Thanh. Organocatalyse énantiosélective par des catalyseurs bifonctionnels : concept et développements. L’Actualité Chimique, 2024, 497, pp.20-23. ⟨hal-04761002⟩ PDF
Stéphane Wittmann, Elodie Deschamps, Chloée Bournaud, Regis Guillot, Jean-François Brière, et al.. Auto tandem triple cascade organocatalysis: Access to bis-lactone and butenolide derivatives. Chemical Communications, 2024, 60, pp.9278-9281. ⟨10.1039/D4CC03029J⟩. ⟨hal-04700648⟩ PDF
Julie Kong, Charlie Lacroix, Chloée Bournaud, Yasuhiro Yamashita, Shū Kobayashi, et al.. Enantioselective Acyl‐Transfer/Protonation Reactions with Designed Chiral Thiourea‐Iminophosphorane Catalysts. Advanced Synthesis and Catalysis, 2024, 366, pp.1101 – 1106. ⟨10.1002/adsc.202301394⟩. ⟨hal-05673756⟩ PDF
Mariia Savchuk, Giang Vo-Thanh, Sylvain Oudeyer, Hélène Beucher, Jean-François Brière. Vinylogous and stereoselective domino synthesis of pyrano[2,3- c ]pyrroles from alkylidene meldrum’s acids. Organic & Biomolecular Chemistry, 2024, ⟨10.1039/D4OB00233D⟩. ⟨hal-04511633⟩ PDF

2023

Pierre Milbeo, Arthur Lebrêne, Mariia Savchuk, Giang Vo-Thanh, Sylvain Oudeyer, et al.. An Organocatalytic and Stereoselective Vinylogous Domino Process Towards Thiochromans. Chemistry – A European Journal, 2023, pp.e202301311. ⟨10.1002/chem.202301311⟩. ⟨hal-04102949⟩ PDF

2022

Martial Toffano, Régis Guillot, Chloée Bournaud, Jean‐françois Brière, Giang Vo-Thanh. Corrigendum: Auto Tandem Catalysis: Asymmetric Vinylogous Cycloaddition/Kinetic Resolution Sequence for the Enantioselective Synthesis of Spiro‐Dihydropyranone from Benzylidene Meldrum’s Acid. Advanced Synthesis and Catalysis, 2022, 364 (7), pp.1345-1345. ⟨10.1002/ADSC.202200152⟩. ⟨hal-05771348⟩

2021

Stéphane Wittmann, Thomas Martzel, Cong Thanh Pham Truong, Martial Toffano, Sylvain Oudeyer, et al.. Alkylidene Meldrum’s Acids as Platforms for the Vinylogous Synthesis of Dihydropyranones. Angewandte Chemie International Edition, 2021, 60, pp.11110-11114. ⟨10.1002/anie.202014489⟩. ⟨hal-03200519⟩ PDF
Martial Toffano, Régis Guillot, Chloee Bournaud, Jean-François Brière, Giang Vo-Thanh. Auto Tandem Catalysis: Asymmetric Vinylogous Cycloaddition / Kinetic Resolution Sequence for the Enantioselective Synthesis of Spiro‐Dihydropyranone from Benzylidene Meldrum’s Acid. Advanced Synthesis and Catalysis, 2021, 363, pp.4452-4458. ⟨10.1002/adsc.202100559⟩. ⟨hal-03304167⟩ PDF
Louis Chassillan, Yasuhiro Yamashita, Woo-Jin Yoo, Martial Toffano, Régis Guillot, et al.. Enantioselective hydrophosphonylation of N -Boc imines using chiral guanidine–thiourea catalysts. Organic & Biomolecular Chemistry, 2021, 19 (48), pp.10560-10564. ⟨10.1039/D1OB01953H⟩. ⟨hal-03815260⟩ PDF
Zhiwei Jiang, Martial Toffano, Giang Vo‐thanh, Chloée Bournaud. Bifunctional N‐Heterocylic Carbene‐Catalyzed Highly Enantioselective Trans‐Cyclopentannulation of Enals and Enones via Homoenolate. ChemCatChem, 2021, 13 (2), pp.712-717. ⟨10.1002/cctc.202001513⟩. ⟨hal-03303929⟩ PDF

2020

Makoto Sako, Romain Losa, Tomohiro Takiishi, Giang Vo-Thanh, Shinobu Takizawa, et al.. Vanadium(V) Complex-Catalyzed One-Pot Synthesis of Phenanthridines via a Pictet-Spengler-Dehydrogenative Aromatization Sequence. Catalysts, 2020, 10, ⟨10.3390/catal10080860⟩. ⟨hal-05684139⟩ PDF
Thanh Tran Duy, Alysson Duarte Rodrigues, Giang Vo-Thanh, Peter Hesemann. Dialkyl imidazolium acetate ionosilica as efficient and recyclable organocatalyst for cyanosilylation reactions of ketones. Green Energy & Environment, 2020, 5 (2), pp.130-137. ⟨10.1016/j.gee.2020.03.005⟩. ⟨hal-02912214⟩ PDF

2019

Thi Thuy Duong Ngo, Khanh Duy Huynh, Houssein Ibrahim, Thi Huong Nguyen, Chloée Bournaud, et al.. Chiral catalysts derived from biomass: design, synthesis and applications in asymmetric catalysis. Vietnam Journal of Chemistry, 2019, 57 (6), pp.670-680. ⟨10.1002/vjch.201900177⟩. ⟨hal-03019278⟩ PDF
Anne-Laure Barthelemy, Elsa Anselmi, Thanh-Nghi Le, Giang Vo-Thanh, Régis Guillot, et al.. Divergent Synthesis of 1,2-Benzo[ e ]thiazine and Benzo[ d ]thiazole Analogues Containing a S -Trifluoromethyl Sulfoximine Group: Preparation and New Properties of the Adachi Reagent. Journal of Organic Chemistry, 2019, 84 (7), pp.4086-4094. ⟨10.1021/acs.joc.9b00079⟩. ⟨hal-02093608⟩ PDF

2018

Lucie Bouchardy, Violeta Rodriguez-Ruiz, Chloée Bournaud, François-Didier Boyer, Martial Toffano, et al.. Novel class of reversible chiral ionic liquids derived from natural amino acids: synthesis and characterization. ChemistrySelect, 2018, 3 (3), pp.958-962. ⟨10.1002/slct.201702708⟩. ⟨hal-01941218⟩
Marina Thierry, Amel A. Majira, Bruce Pegot, Laurent Cezard, Flavien Bourdreux, et al.. Imidazolium‐Based Ionic Liquids as Efficient Reagents for the C−O Bond Cleavage of Lignin. ChemSusChem, 2018, 11 (2), pp.439-448. ⟨10.1002/cssc.201701668⟩. ⟨hal-01817782⟩ PDF

2017

Duc Dung Pham, Ngoc Thach Le, Giang Vo-Thanh. Fast and Efficient Hantzsch Synthesis Using Acid‐Activated and Cation‐Exchanged Montmorillonite Catalysts under Solvent‐Free Microwave Irradiation Conditions. ChemistrySelect, 2017, 2 (36), pp.12041-12045. ⟨10.1002/slct.201702681⟩. ⟨hal-05684234⟩

2016

Thi‐thuy‐duong Ngo, Kenta Kishi, Makoto Sako, Masashi Shigenobu, Chloée Bournaud, et al.. Organocatalyzed [4+2] Annulation of All‐Carbon Tetrasubstituted Alkenes with Allenoates: Synthesis of Highly Functionalized 2 H ‐ and 4 H ‐Pyran Derivatives.. ChemistrySelect, 2016, 1 (17), pp.5414-5420. ⟨10.1002/SLCT.201601204⟩. ⟨hal-05770949⟩
Thanh-Nghi Le, Patrick Diter, Bruce Pégot, Chloée Bournaud, Martial Toffano, et al.. S -Trifluoromethyl Sulfoximine as a Directing Group in Ortho -Lithiation Reaction toward Structural Complexity. Organic Letters, 2016, 18 (19), pp.5102-5105. ⟨10.1021/acs.orglett.6b02548⟩. ⟨hal-05130984⟩
Thi‐thuy‐duong Ngo, Thi‐huong Nguyen, Chloée Bournaud, Régis Guillot, Martial Toffano, et al.. Phosphine–Thiourea‐Organocatalyzed Asymmetric C−N and C−S Bond Formation Reactions. Asian Journal of Organic Chemistry, 2016, 5 (7), pp.895-899. ⟨10.1002/AJOC.201600212⟩. ⟨hal-05770947⟩

2015

Thanh-Nghi Le, Patrick Diter, Bruce Pégot, Chloée Bournaud, Martial Toffano, et al.. Functionalized S-perfluorinated sulfoximines: Preparation and evaluation in catalytic processes. Journal of Fluorine Chemistry, 2015, 179, pp.179-187. ⟨10.1016/j.jfluchem.2015.06.020⟩. ⟨hal-05131389⟩
Ngoc Ngo, Thi Tran, Thi Dinh, Giang Vo-Thanh, Stéphanie Legoupy. Synthesis of Novel Triazolo Cyclobutane Nucleoside Analogs. Bulletin of the Korean Chemical Society, 2015, 36 (5), pp.1390-1395. ⟨10.1002/bkcs.10270⟩. ⟨hal-01308807⟩

2014

Thanh-Nghi Le, Emilie Kolodziej, Patrick Diter, Bruce Pégot, Chloée Bournaud, et al.. First Isolation of Enantiopure Perfluoroalkylated Sulfilimines and Sulfoximines. CHIMIA, 2014, 68 (6), pp.410. ⟨10.2533/chimia.2014.410⟩. ⟨hal-05121417⟩ PDF

2013

Amélia Thomasset, Lucie Bouchardy, Chloée Bournaud, Régis Guillot, Martial Toffano, et al.. Synthesis and Characterization of New Chiral Azolinium Salts, Precursors to N-Heterocyclic Carbenes, Derived from l-Proline. Synthesis: Journal of Synthetic Organic Chemistry, 2013, 46 (02), pp.242-250. ⟨10.1055/S-0033-1340215⟩. ⟨hal-05770809⟩
Yohan Macé, Céline Constant-Urban, Sébastien Bouvet, Bruce Pégot, Chloée Bournaud, et al.. A Mild and Efficient Procedure for the N-Functionalization of S-Perfluoroalkylated Aryl Sulfoximines. Synthesis: Journal of Synthetic Organic Chemistry, 2013, 45 (11), pp.1505-1512. ⟨10.1055/s-0033-1338440⟩. ⟨hal-05131369⟩

2012

Houssein Ibrahim, Chloée Bournaud, Régis Guillot, Martial Toffano, Giang Vo-Thanh. Synthesis of novel chiral monophosphine ligands derived from isomannide and isosorbide. Application to enantioselective hydrogenation of olefins. Tetrahedron Letters, 2012, 53 (36), pp.4900-4902. ⟨10.1016/J.TETLET.2012.07.035⟩. ⟨hal-05770687⟩

2011

Yohan Macé, Bruce Pégot, Régis Guillot, Chloée Bournaud, Martial Toffano, et al.. Efficient copper-induced coupling between NH-fluoroalkylated sulfoximines and aryl iodides or bromides. Tetrahedron, 2011, 67 (39), pp.7575-7580. ⟨10.1016/j.tet.2011.07.060⟩. ⟨hal-05123370⟩

2007

Olivier Nguyen van Buu, Giang Vo-Thanh. Synthesis of Novel Chiral Ammonium-Based Ionic Liquids Derived from Isosorbide and their Applications in an Asymmetric Aza Diels-Alder Reaction. Letters in Organic Chemistry, 2007, 4 (3), pp.158-167. ⟨10.2174/157017807780737219⟩. ⟨hal-05684480⟩

2006

Bruce Pégot, Olivier Nguyen van Buu, Didier Gori, Giang Vo-Thanh. Asymmetric aza-Diels-Alder reaction of Danishefsky’s diene with imines in a chiral reaction medium. Beilstein Journal of Organic Chemistry, 2006, 2, pp.18. ⟨10.1186/1860-5397-2-18⟩. ⟨hal-05684481⟩ PDF

2004

Mickaël Montembault, Giang Vo-Thanh, Abdallah Deyine, Valérie Fargeas, Monique Villiéras, et al.. A possible improvement for structure-based drug design illustrated by the discovery of a Tat HIV-1 inhibitor. Bioorganic and Medicinal Chemistry Letters, 2004, 14 (6), pp.1543-1546. ⟨10.1016/j.bmcl.2003.12.095⟩. ⟨hal-02137964⟩

1999

F.D. Boyer, Josiane Beauhaire, – Giang Vo Thanh, C. Descoins, Martine Lettere, et al.. Use of natural products in pest management ; Synthetic studies on pheromones and antifeedants. Recent Research Developments in Synthetic Organic Chemistry, 1999, 2, pp.49-67. ⟨hal-02695763⟩
C. Descoins, – Giang Vo Thanh, F.D. Boyer, Paul Henri Ducrot, C. Descoins, et al.. Synthesis of polydydroxylated decalins; a new strategy toward the total synthesis of agarfuran antifeedants. SYNLETT, 1999, 2, pp.240-242. ⟨hal-02685661⟩

Conference papers

1998

C. Descoins, G. Vo Thanh, F.D. Boyer, C. Descoins, Paul Henri Ducrot. Chimie des antiappétents : Approche synthétique des sesquiterpènes de la famille des agarofuranes. JCO 98, Sep 1998, Palaiseau, France. ⟨hal-02766319⟩
C. Descoins, G. Vo Thanh, Paul Henri Ducrot, F.D. Boyer. Antifeedants chemistry: Towards the synthesis of agarofuranes sesquiterpenes. 9. International congress, Aug 1998, Londres, United Kingdom. ⟨hal-02771870⟩

Poster communications

2018

M Thierry, A Majira, B Pégot, L Cézard, F Bourdreux, et al.. Production of lignin-derived phenolics through ionic liquids-based treatments. 4th WORKSHOP & 5th MC MEETING of COST LIGNOVAL, Mar 2018, Thessaloniki, Greece. ⟨hal-04516960⟩ PDF