Journal articles

2026

Guillaume Schoenn, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Diversification of the Avarane Skeleton Toward Spiroetherone A. ChemistryEurope, 2026, 4 (9), pp.e70350. ⟨10.1002/ceur.70350⟩. ⟨hal-05770600⟩

Wei Cao, Alicia Ross, Jean‐pierre Baltaze, Régis Guillot, Menglin Xu, et al.. Toward the Synthesis of Pestalustaine A: Structural Revision and Formation of Original Strained Tricyclic Architectures. Angewandte Chemie International Edition, 2026, 65 (37), pp.e7194437. ⟨10.1002/anie.7194437⟩. ⟨hal-05688259⟩

Dang Khoi Duong, Cyrille Kouklovsky, Valérie Alezra, Aurélien de la Torre. Recent Advances in Axial Chirality Construction by Cycloaddition. Synthesis: Journal of Synthetic Organic Chemistry, 2026, 58 (16), pp.1823-1854. ⟨10.1055/a-2888-8865⟩. ⟨hal-05797068⟩

Haoqi Zhang, Cyrille Kouklovsky, Aurélien de la Torre. Recent Approaches for the Synthesis of Lucidumone. European Journal of Organic Chemistry, 2026, 29 (16), ⟨10.1002/ejoc.70395⟩. ⟨hal-05797065⟩

Elisa Coll, Vincent Gandon, Cyrille Kouklovsky, Laurent Evanno, Guillaume Vincent. Total Synthesis of the Spirocyclic Bis‐Indole Alkaloid (−)‐Owerreine via a [4+2] Annulation. Angewandte Chemie International Edition, 2026, 17 (65), pp.e4281634. ⟨10.1002/anie.4281634⟩. ⟨hal-05589026⟩

2025

Bocheng Chen, Lucas Pagès, Cyrille Kouklovsky, Sébastien Prévost, Aurélien de la Torre. Chemoselective Double Allylic Substitutions with Carbon Nucleophiles: Access to Tetrahydroindoles and Tetrahydrocarbazoles. Journal of Organic Chemistry, 2025, 90 (17), pp.6079-6083. ⟨10.1021/acs.joc.5c00121⟩. ⟨hal-05353483⟩

Guillaume Schoenn, Cyrille Kouklovsky, Régis Guillot, Thomas Magauer, Guillaume Vincent. Total Synthesis of Dactyloquinone A and Spiroetherone A via a Metal‐Hydride Hydrogen Atom Transfer (MHAT) Process and a Quinol–Enedione Rearrangement. Angewandte Chemie International Edition, 2025, 64 (25), pp.e202505270. ⟨10.1002/anie.202505270⟩. ⟨hal-05348489⟩

Antoine Lefevre, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Synthesis of γ-Lactones from the Intermolecular Oxidative Coupling between Malonates and Styrenes. Journal of Organic Chemistry, 2025, 90 (12), pp.4450-4457. ⟨10.1021/acs.joc.5c00228⟩. ⟨hal-05117275⟩

Nicolas Fay, Camil C Benbouziyane, Cyrille Kouklovsky, Aurélien de la Torre. Synthesis of a Functionalized Bicyclo[3.2.1]Octane: A Common Subunit to Kauranes, Grayananes, and Gibberellanes. Chemistry – A European Journal, 2025, 31 (64), pp.e02441. ⟨10.1002/chem.202502441⟩. ⟨hal-05503828⟩

2024

Bocheng Chen, Lucas Pagès, Raphaël Dollet, Cyrille Kouklovsky, Sébastien Prévost, et al.. Regio-and Chemoselective Double Allylic Substitution of Alkenyl vic-Diols. Organic Letters, 2024, 26 (12), pp.2393-2397. ⟨10.1021/acs.orglett.4c00495⟩. ⟨hal-04727504⟩

Antoine Lefevre, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Ferrocene-Mediated Electrochemical Polycyclization of Malonates. Organic Letters, 2024, 26 (35), pp.521-534. ⟨10.1021/acs.orglett.4c02727⟩. ⟨hal-04762091⟩

Guangho Huang, Amaury Laporte, Lucas Pagès, Cyrille Kouklovsky, Aurélien de la Torre. Total Synthesis of Lucidumone: Attempted Shortcuts, Dead-Ends and Lessons Learnt. Synthesis: Journal of Synthetic Organic Chemistry, 2024, 56 (10), pp.1585-1592. ⟨10.1055/s-0042-1751529⟩. ⟨hal-04727494⟩

Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, Guillaume Vincent. Total Synthesis of Mavacuran Alkaloids with Bioinspired and non-Bioinspired Strategies. SYNLETT, 2024, 35 (5), pp.521-534. ⟨10.1055/s-0042-1751498⟩. ⟨hal-04274139⟩

2023

Nicolas Fay, Cyrille Kouklovsky, Aurélien de La Torre. Natural Product Synthesis: the Endless Quest for an Unreachable Perfection. ACS Organic & Inorganic Au, 2023, 3 (6), pp.350-363. ⟨10.1021/acsorginorgau.3c00040⟩. ⟨hal-04727481⟩

Guanghao Huang, Cyrille Kouklovsky, Aurélien de la Torre. Retro-[4+2]/Intramolecular Diels–Alder Cascade Allows a Concise Total Synthesis of Lucidumone. SYNLETT, 2023, 34 (11), pp.1195-1199. ⟨10.1055/s-0042-1751412⟩. ⟨hal-04240630⟩

Flavie Rambaud, Régis Guillot, Valérie Alezra, Cyrille Kouklovsky. Diversity in the Synthesis of Functionalized Cyclohexene Oxide Derivatives by a Cycloaddition–Fragmentation Sequence from Benzene Oxide. Journal of Organic Chemistry, 2023, 88 (11), pp.7152-7161. ⟨10.1021/ACS.JOC.3C00398⟩. ⟨hal-05771615⟩

Leandro C. Tabares, Davis T. Daniel, José Luis Vázquez-Ibar, Cyrille Kouklovsky, Valérie Alezra, et al.. Using the noncanonical metallo-amino Acid [Cu(II)(2,2′-Bipyridin-5-yl)]-alanine to study the structures of proteins. Journal of Physical Chemistry Letters, 2023, 14 (14), pp.3368-3375. ⟨10.1021/acs.jpclett.3c00196⟩. ⟨hal-04297922⟩

Audrey Mauger, Maxime Jarret, Aurélien Tap, Rémi Perrin, Régis Guillot,, et al.. Collective Total Synthesis of Mavacuran Alkaloids via an Intermo-lecular 1,4-Addition Approach. Angewandte Chemie International Edition, 2023, 62, ⟨10.1002/anie.202302461⟩. ⟨hal-04274088⟩

2022

Nicolas Fay, Rémi Blieck, Cyrille Kouklovsky, Aurélien de la Torre. Total synthesis of grayanane natural products. Beilstein Journal of Organic Chemistry, 2022, 18, pp.1707 – 1719. ⟨10.3762/bjoc.18.181⟩. ⟨hal-04240623⟩

Guanghao Huang, Régis Guillot,, Cyrille Kouklovsky, Boris Maryasin, Aurélien de la Torre. Diastereo‐ and Enantioselective Inverse‐Electron‐Demand Diels–Alder Cycloaddition between 2‐Pyrones and Acyclic Enol Ethers. Angewandte Chemie International Edition, 2022, 61 (42), ⟨10.1002/anie.202208185⟩. ⟨hal-03845712⟩

Guanghao Huang, Cyrille Kouklovsky, Aurélien de la Torre. Gram-Scale Enantioselective Synthesis of (+)-Lucidumone. Journal of the American Chemical Society, 2022, 144 (39), pp.17803-17807. ⟨10.1021/jacs.2c08760⟩. ⟨hal-03845727⟩

Anaïs Rousseau, Guillaume Vincent, Cyrille Kouklovsky. Preparation of an advanced intermediate for the synthesis of leustroducsins and phoslactomycins by heterocycloaddition. Beilstein Journal of Organic Chemistry, 2022, 18, pp.1385-1395. ⟨10.3762/bjoc.18.143⟩. ⟨hal-03838971⟩

Wei Cao, Yingchao Dou, Cyrille Kouklovsky, Guillaume Vincent. Total Synthesis of Ophiorrhine A, G and Ophiorrhiside E Featuring a Bioinspired Intramolecular Diels–Alder Cycloaddition. Angewandte Chemie International Edition, 2022, 61 (38), pp.e202209135. ⟨10.1002/anie.202209135⟩. ⟨hal-03837639⟩

2021

Loïc Roupnel, Régis Guillot, Didier Gori, Baby Viswambharan, Cyrille Kouklovsky, et al.. Highly stereoselective aldol reactions by Memory of Chirality: synthesis of quaternary beta-hydroxy alpha-amino acids. Helvetica Chimica Acta, 2021, 104 (10), ⟨10.1002/hlca.202100127⟩. ⟨hal-03576201⟩

Guanghao Huang, Cyrille Kouklovsky, Aurélien de La Torre. Inverse-Electron-Demand Diels-Alder Reactions of 2-Pyrones: Bridged Lactones and Beyond. Chemistry – A European Journal, 2021, 27 (15), pp.4760-4788. ⟨10.1002/chem.202003980⟩. ⟨hal-03024430⟩

Maxime Jarret, Hussein Abou-Hamdan, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Bioinspired Early Divergent Oxidative Cyclizations toward Pleiocarpamine, Talbotine, and Strictamine. Organic Letters, 2021, 23 (4), pp.1355-1360. ⟨10.1021/acs.orglett.1c00018⟩. ⟨hal-03186900⟩

Audrey Mauger, Maxime Jarret, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. The chemistry of mavacurane alkaloids: a rich source of bis-indole alkaloids. Natural Product Reports, 2021, 30 (10), pp.1852-1886. ⟨10.1039/D0NP00088D⟩. ⟨hal-03186969⟩

Hussein Abou-Hamdan, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of a Seco iso -Secologanin Aglycone Analogue of Interest toward Secoiridoids and Monoterpene Indole Alkaloids. Journal of Organic Chemistry, 2021, 86 (13), pp.9244-9252. ⟨10.1021/acs.joc.1c00916⟩. ⟨hal-03286160⟩

2020

Yingchao Dou, Cyrille Kouklovsky, Guillaume Vincent. Bioinspired Divergent Oxidative Cyclization from Strictosidine and Vincoside Derivatives: Second Generation Total Synthesis of Cymoside and Access to an Original Hexacyclic‐Fused Furo[3,2‐b]indoline. Chemistry – A European Journal, 2020, 26 (71), pp.17190-17194. ⟨10.1002/chem.202003758⟩. ⟨hal-02960522⟩

Maxime Jarret, Aurélien Tap, Victor Turpin, Natacha Denizot, Cyrille Kouklovsky, et al.. Bioinspired Divergent Oxidative Cyclizations of Geissoschizine: Total Synthesis of (–)‐17‐nor‐Excelsinidine, (+)‐16‐epi‐Pleiocarpamine, (+)‐16‐Hydroxymethyl‐Pleiocarpamine and (+)‐Taberdivarine H. European Journal of Organic Chemistry, 2020, 40, pp.6340-6351. ⟨10.1002/ejoc.202000962⟩. ⟨hal-02960543⟩

Ju Wu, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Dearomative Dihydroxylation and Hydroxycyclization of Indoles. Advanced Synthesis and Catalysis, 2020, 362 (8), pp.1712-1719. ⟨10.1002/adsc.202000158⟩. ⟨hal-02960497⟩

Ju Wu, Hussein Abou-Hamdan, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical synthesis of 3a-bromofuranoindolines and 3a-bromopyrroloindolines mediated by MgBr 2. Chemical Communications, 2020, 56 (11), pp.1713-1716. ⟨10.1039/C9CC09276E⟩. ⟨hal-02960483⟩

Yingchao Dou, Cyrille Kouklovsky, Vincent Gandon, Guillaume Vincent. Enantioselective Total Synthesis of Cymoside through a Bioinspired Oxidative Cyclization of a Strictosidine Derivative. Angewandte Chemie International Edition, 2020, 59 (4), pp.1527-1531. ⟨10.1002/anie.201912812⟩. ⟨hal-02471140⟩

Hussein Abou-Hamdan, Cyrille Kouklovsky, Guillaume Vincent. Dearomatization Reactions of Indoles to Access 3D Indoline Structures. SYNLETT, 2020, 31 (18), pp.1775-1788. ⟨10.1055/s-0040-1707152⟩. ⟨hal-02960505⟩

2019

Maxime Jarret, Victor Turpin, Aurélien Tap, Jean-François Gallard, Cyrille Kouklovsky, et al.. Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for Enantioselective Total Synthesis of Mavacuran Alkaloids. Angewandte Chemie International Edition, 2019, 58 (29), pp.9861-9865. ⟨10.1002/anie.201905227⟩. ⟨hal-02322586⟩

Ju Wu, Yingchao Dou, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Electrochemical Dearomative 2,3-Difunctionalization of Indoles. Journal of the American Chemical Society, 2019, 141 (7), pp.2832-2837. ⟨10.1021/jacs.8b13371⟩. ⟨hal-02322510⟩

Yang Wan, Jean-Pierre Baltaze, Cyrille Kouklovsky, Emeric Miclet, Valérie Alezra. Unexpected dimerization of a tripeptide comprising a β,γ-diamino acid. Journal of Peptide Science, 2019, 25 (2), pp.e3143. ⟨10.1002/psc.3143⟩. ⟨hal-03989036⟩

Dmytro Ryzhakov, Maxime Jarret, Jean-Pierre J.-P. Baltaze, Régis Guillot, Cyrille Kouklovsky, et al.. Synthesis of 3,3-Spirocyclic 2-Phosphonoindolines via a Dearomative Addition of Phosphonyl Radicals to Indoles. Organic Letters, 2019, 21 (13), pp.4986-4990. ⟨10.1021/acs.orglett.9b01516⟩. ⟨hal-02322542⟩

2018

Natacha Denizot, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. N-Iodosuccinimide-Mediated Oxidative Coupling of Indoles and Phenols: A Synthetic Study toward the Benzofuroindoline Moiety of Bipleiophylline. Synthesis: Journal of Synthetic Organic Chemistry, 2018, 50 (24), pp.4823-4828. ⟨10.1055/s-0036-1592002⟩. ⟨hal-02348825⟩

Natacha Denizot, David Lachkar, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Divergent Oxidative Couplings between Indoles and 2,3-Dihydroxybenzoic Acid Derivatives for the Biomimetic Synthesis of Voacalgine A and Bipleiophylline. Synthesis: Journal of Synthetic Organic Chemistry, 2018, 50 (21), pp.4229-4242. ⟨10.1055/s-0036-1591910⟩. ⟨hal-02348831⟩

Maxime Jarret, Aurélien Tap, Cyrille Kouklovsky, Erwan Poupon, Laurent Evanno, et al.. Bioinspired Oxidative Cyclization of the Geissoschizine Skeleton for the Total Synthesis of (−)-17-nor-Excelsinidine. Angewandte Chemie International Edition, 2018, 57 (38), pp.12294-12298. ⟨10.1002/anie.201802610⟩. ⟨hal-02348789⟩

Yang Wan, Andrii Stanovych, Didier Gori, Séverine Zirah, Cyrille Kouklovsky, et al.. β,γ-diamino acids as building blocks for new analogues of Gramicidin S: Synthesis and biological activity. European Journal of Medicinal Chemistry, 2018, 149, pp.122-128. ⟨10.1016/j.ejmech.2018.02.053⟩. ⟨hal-02912576⟩

Ju Wu, Raj Kumar Nandi, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Dearomative Diallylation of N -Acylindoles Mediated by FeCl 3. Organic Letters, 2018, 20 (7), pp.1845-1848. ⟨10.1021/acs.orglett.8b00361⟩. ⟨hal-02348801⟩

Rémy Campagne, Friederike Schäkel, Régis Guillot, Valérie Alezra, Cyrille Kouklovsky. Base-Mediated Fragmentation of Bicyclic Dihydro-3,6-oxazines: Transformation of Nitroso Diels–Alder Cycloadducts. Organic Letters, 2018, 20 (7), pp.1884-1887. ⟨10.1021/ACS.ORGLETT.8B00426⟩. ⟨hal-05771081⟩

Yang Wan, Nicolas Auberger, Sophie Thétiot-Laurent, Francelin Bouillère, Anaïs Zulauf, et al.. Constrained Cyclic β,γ-Diamino Acids from Glutamic Acid: Synthesis of Both Diastereomers and Unexpected Kinetic Resolution. European Journal of Organic Chemistry, 2018, 2018 (3), pp.329-340. ⟨10.1002/ejoc.201701477⟩. ⟨hal-02997993⟩

Raj Kumar Nandi, Alejandro Perez-Luna, Didier Gori, Rodolphe Beaud, Régis Guillot, et al.. Triflic Acid as an Efficient Brønsted Acid Promoter for the Umpolung of N-Ac Indoles in Hydroarylation Reactions. Advanced Synthesis and Catalysis, 2018, 360 (1), pp.161-172. ⟨10.1002/adsc.201701074⟩. ⟨hal-02348844⟩

Antonin Mambrini, Didier Gori, Régis Guillot, Cyrille Kouklovsky, Valérie Alezra. Oxidative coupling of enolates using memory of chirality: an original enantioselective synthesis of quaternary α-amino acid derivatives. Chemical Communications, 2018, 54 (90), pp.12742-12745. ⟨10.1039/C8CC06864J⟩. ⟨hal-05771063⟩

2017

Anaïs Rousseau, Marie Buchotte, Régis Guillot, Guillaume Vincent, Cyrille Kouklovsky. Expedient Approach to α,β‐Unsaturated δ‐Lactones through a Catalytic Asymmetric [2+2] Cycloaddition. European Journal of Organic Chemistry, 2017, 2017 (45), pp.6804-6810. ⟨10.1002/EJOC.201701336⟩. ⟨hal-05771017⟩

Dmytro Ryzhakov, Maxime Jarret, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Radical-Mediated Dearomatization of Indoles with Sulfinate Reagents for the Synthesis of Fluorinated Spirocyclic Indolines. Organic Letters, 2017, 19 (23), pp.6336-6339. ⟨10.1021/ACS.ORGLETT.7B03155⟩. ⟨hal-05771003⟩

David Lachkar, Natacha Denizot, Guillaume Bernadat, Kadiria Ahamada, Mehdi Beniddir, et al.. Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings. Nature Chemistry-, 2017, 9 (8), pp.793-798. ⟨10.1038/nchem.2735⟩. ⟨hal-05115363⟩

Terry Tomakinian, Hussein Abou Hamdan, Natacha Denizot, Régis Guillot,, Jean-Pierre Baltaze, et al.. Evaluation of an NIS-Mediated Oxidative Cyclisation of Phenol-Containing N-Acyltryptamine Precursors towards Phalarine: Synthesis of 4 ‘,5 ‘-Dihydrospiro[indole-3,6 ‘-[1,3]oxazine]s. European Journal of Organic Chemistry, 2017, 2017 (19), pp.2757-2763. ⟨10.1002/ejoc.201601563⟩. ⟨hal-05255498⟩

Thi Thoa Mai, Baby Viswambharan, Didier Gori, Régis Guillot, Jean‐valère Naubron, et al.. Frozen Chirality of Tertiary Aromatic Amides: Access to Enantioenriched Tertiary α‐Amino Acid or Amino Alcohol without Chiral Reagent. Chemistry – A European Journal, 2017, 23 (24), pp.5787-5798. ⟨10.1002/CHEM.201700110⟩. ⟨hal-05771015⟩

Rodolphe Beaud, Raj Kumar Nandi, Alejandro Perez-Luna, Régis Guillot, Didier Gori, et al.. Revealing the electrophilicity of N-Ac indoles with FeCl _\textrm3 : a mechanistic study. Chemical Communications, 2017, 53 (43), pp.5834–5837. ⟨10.1039/C7CC02756G⟩. ⟨hal-01712357⟩

2016

Nicolas Auberger, Andrii Stanovych, Sophie Thétiot-Laurent, Régis Guillot, Cyrille Kouklovsky, et al.. Efficient synthesis of both diastereomers of β,γ-diamino acids from phenylalanine and tryptophan. Amino Acids, 2016, 48 (9), pp.2237–2242. ⟨10.1007/s00726-016-2262-8⟩. ⟨hal-01460662⟩

Raj Kumar Nandi, Friederike Ratsch, Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, et al.. Intermolecular dearomative C2-arylation of N-Ac indoles activated by FeCl 3. Chemical Communications, 2016, 52 (30), pp.5328-5331. ⟨10.1039/C6CC01654E⟩. ⟨hal-05770958⟩

Terry Tomakinian, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of benzofuro[3,2-b]indoline amines via deamination-interrupted Fischer indolization and their unexpected reactivity towards nucleophiles. Chemical Communications, 2016, 52 (31), pp.5443-5446. ⟨10.1039/C6CC00365F⟩. ⟨hal-05770941⟩

Raj Kumar Nandi, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Synthesis of 3,3-Spiroindolines via FeCl 3 -Mediated Cyclisation of Aryl or Alkene-Containing 3-Substituted N-Ac Indoles. Organic Letters, 2016, 18 (8), pp.1716-1719. ⟨10.1021/acs.orglett.6b00174⟩. ⟨hal-01509939⟩

2015

Natacha Denizot, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Connecting Tyrosine and Tryptophan Units of Diazonamide A and Azonazine by a Diastereodivergent Arylative Dearomatization. Chemistry – A European Journal, 2015, 21 (52), pp.18953-18956. ⟨10.1002/CHEM.201503612⟩. ⟨hal-05770912⟩

2014

Natacha Denizot, Annie Pouilhès, Mélissa Cucca, Rodolphe Beaud, Régis Guillot, et al.. Bioinspired Direct Access to Benzofuroindolines by Oxidative [3 + 2] Annulation of Phenols and Indoles. Organic Letters, 2014, 16 (21), pp.5752-5755. ⟨10.1021/OL502820P⟩. ⟨hal-05770847⟩

Andrii Stanovych, Régis Guillot, Cyrille Kouklovsky, Emeric Miclet, Valérie Alezra. β,γ-Diamino acid: an original building block for hybrid α/γ-peptide synthesis with extra hydrogen bond donating group.. Amino Acids, 2014, 46 (12), pp.2753-2757. ⟨10.1007/s00726-014-1831-y⟩. ⟨hal-01064605⟩

Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. Regioselective Hydroarylation Reactions of C3 Electrophilic N ‐Acetylindoles Activated by FeCl 3 : An Entry to 3‐(Hetero)arylindolines. Chemistry – A European Journal, 2014, 20 (24), pp.7492-7500. ⟨10.1002/CHEM.201400284⟩. ⟨hal-05770816⟩

Baby Viswambharan, Didier Gori, Régis Guillot, Cyrille Kouklovsky, Valérie Alezra. Substrate Control in Enantioselective and Diastereoselective Aldol Reaction by Memory of Chirality: A Rapid Access to Enantiopure β-Hydroxy Quaternary α-Amino Acids. Organic Letters, 2014, 16 (3), pp.788-791. ⟨10.1021/OL403523E⟩. ⟨hal-05770812⟩

2012

Sophie Thétiot-Laurent, Francelin Bouillère, Jean-Pierre Baltaze, François Brisset, Debby Feytens, et al.. Original β,γ-diamino acid as an inducer of a γ-turn mimic in short peptides.. Organic & Biomolecular Chemistry, 2012, 10, pp.9660-9663. ⟨10.1039/c2ob26828k⟩. ⟨hal-00751282⟩

Rodolphe Beaud, Régis Guillot, Cyrille Kouklovsky, Guillaume Vincent. FeCl 3 ‐Mediated Friedel–Crafts Hydroarylation with Electrophilic N ‐Acetyl Indoles for the Synthesis of Benzofuroindolines. Angewandte Chemie International Edition, 2012, 51 (50), pp.12546-12550. ⟨10.1002/ANIE.201206611⟩. ⟨hal-05770716⟩

Thi Thoa Mai, Mathieu Branca, Didier Gori, Régis Guillot, Cyrille Kouklovsky, et al.. Absolute Asymmetric Synthesis of Tertiary α‐Amino Acids. Angewandte Chemie International Edition, 2012, 51 (20), pp.4981-4984. ⟨10.1002/ANIE.201200950⟩. ⟨hal-05770731⟩

Francelin Bouillère, Debby Feytens, Didier Gori, Régis Guillot, Cyrille Kouklovsky, et al.. Constrained α/γ-peptides: a new stable extended structure in solution without any hydrogen bond and characterized by a four-fold symmetry.. Chemical Communications, 2012, 48 ((14)), pp.1982-4. ⟨10.1039/c2cc16852a⟩. ⟨hal-00680908⟩

2011

Francelin Bouillère, Régis Guillot, Cyrille Kouklovsky, Valérie Alezra. Access to β,γ-diamino acids. Application to the synthesis of 3-deoxyaminostatine. Organic & Biomolecular Chemistry, 2011, 9 (2), pp.394-399. ⟨10.1039/c0ob00370k⟩. ⟨hal-05773225⟩

Bouillère Francellin, Sophie Thétiot-Laurent, Cyrille Kouklovsky, Valérie Alezra. Foldamers containing gamma-amino acid residues or their analogues: structural features and applications. Amino Acids, 2011, 41, pp.687-707. ⟨10.1007/s00726-011-0893-3⟩. ⟨hal-01244475⟩

Guillaume Vincent, Régis Guillot, Cyrille Kouklovsky. Stereodivergent Synthesis of Substituted N,O‐Containing Bicyclic Compounds by Sequential Addition of Nucleophiles to N ‐Alkoxybicyclolactams. Angewandte Chemie International Edition, 2011, 50 (6), pp.1350-1353. ⟨10.1002/ANIE.201006590⟩. ⟨hal-05769771⟩

2009

Mathieu Branca, Sébastien Pena, Régis Guillot, Didier Gori, Valérie Alezra, et al.. Memory of Chirality of Tertiary Aromatic Amides: A Simple and Efficient Method for the Enantioselective Synthesis of Quaternary α-Amino Acids. Journal of the American Chemical Society, 2009, 131 (30), pp.10711-10718. ⟨10.1021/JA9039604⟩. ⟨hal-05769713⟩

2008

Mathieu Branca, Didier Gori, Régis Guillot, Valérie Alezra, Cyrille Kouklovsky. Tertiary Aromatic Amide for Memory of Chirality: Access to Enantioenriched α-Substituted Valine. Journal of the American Chemical Society, 2008, 130 (18), pp.5864-5865. ⟨10.1021/JA801165Z⟩. ⟨hal-05769656⟩

2007

Cam Thuy Hoang, Valérie Alezra, Régis Guillot, Cyrille Kouklovsky. A Stereoselective Entry into Functionalized 1,2-Diamines by Zinc-Mediated Homologation of α-Aminoacids. Organic Letters, 2007, 9 (13), pp.2521-2524. ⟨10.1021/OL0708020⟩. ⟨hal-05769646⟩

Géraldine Calvet, Nicolas Blanchard, Cyrille Kouklovsky, Régis Guillot. 2,2-Dimethyl-5-nitroso-1,3-dioxan-5-yl benzoate, 2,2-dimethyl-5-nitroso-1,3-dioxan-5-yl 4-chlorobenzoate and 5-nitroso-1,3-dioxan-5-yl 4-chlorobenzoate. Acta Crystallographica Section C : Crystal Structure Communications [1968-2013], 2007, 63 (6), pp.o365-o368. ⟨10.1107/S0108270107021804⟩. ⟨hal-05769647⟩

2005

Géraldine Calvet, Régis Guillot, Nicolas Blanchard, Cyrille Kouklovsky. Intermolecular nitroso Diels–Alder cycloaddition of α-acetoxynitroso derivatives in aqueous medium. Organic & Biomolecular Chemistry, 2005, 3 (24), pp.4395. ⟨10.1039/B513397A⟩. ⟨hal-05769584⟩

1999

Olivier Dirat, Cyrille Kouklovsky, Yves Langlois, Philippe Lesot, Jacques Courtieu. Double diastereoselection in asymmetric [2+3] cycloaddition of chiral oxazoline N-oxides: application to the kinetic resolution of a racemic α,β-unsaturated δ-lactone. Tetrahedron: Asymmetry, 1999, 10 (16), pp.3197-3207. ⟨10.1016/S0957-4166(99)00317-1⟩. ⟨hal-02309107⟩

Poster communications

2022

Bocheng Chen, Cyrille Kouklovsky, Sébastien Prévost, Aurélien de La Torre. Allyl double substitution of vicinal alkenyl diols. Journées de Chimie Organique 2022, Nov 2022, Palaiseau, France. ⟨hal-04315301⟩

Pre-publications

2026

Camil Benbouziyane, Régis Guillot, Cyrille Kouklovsky, Aurélien de la Torre. Total Synthesis of Piperhancin B and Isofutoquinol. 2026. ⟨hal-05789004⟩