
Institut de Chimie Moléculaire et des Matériaux d Orsay
Bat 670
17 Av. des Sciences
91190 Orsay
Dominique Urban
Bioorganic and Bioinorganic Chemistry, NMR Methodology
0169157135, room 1202
Journal articles
2026
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- Océane Monfret, Dan Liu, Manon Louis, Sihem Rebei, Dominique Urban, et al.. Synthesis and Evaluation of the First Generation of Glycosylated Nucleoside Analogues as Potential Inhibitors of the Base J Metabolism in Kinetoplastid Parasites. Chemistry – A European Journal, In press, ⟨10.1002/chem.202503227⟩. ⟨hal-05457928⟩
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2025
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- Emilie Lesur, Yijie Zhang, Nathalie Dautin, Christiane Dietrich, Ines Li de la Sierra-Gallay, et al.. Synthetic mycolates derivatives to decipher protein mycoloylation, a unique post-translational modification in bacteria. Journal of Biological Chemistry, In press, ⟨10.1016/j.jbc.2025.108243⟩. ⟨hal-04917545⟩
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- Mathilde Pucher, Kirrthana Makenthirathasan, Hadrien Jalaber, Thomas Lesaux, Oliver Nüsse, et al.. Borinic Acid-Based Fluorogenic Probes as an Alternative to the Amplex Red Assay for Real-Time H 2 O 2 Monitoring in Live Cells. ACS Chemical Biology, 2025, 20 (7), pp.1574-1583. ⟨10.1021/acschembio.5c00156⟩. ⟨hal-05250768⟩
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- Paulin Rollando, Emilie Lesur, Dominique Urban, Gilles Doisneau, Dominique Guianvarc’h, et al.. Synthesis of Bioorthogonal Mycolic Acids: Chemoselective Reduction of β‐Ketoesters Containing an Alkyne Using the Noyori Catalyst. European Journal of Organic Chemistry, 2025, 28 (41), pp.e202500642. ⟨10.1002/ejoc.202500642⟩. ⟨hal-05262592⟩
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2024
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- Ander Ander Camiruaga, Alexandra Gouasmat, Jean-Marie Beau, Yann Bourdreux, Maélie Causse, et al.. Mixing water, sugar, and lipid: Conformations of isolated and micro-hydrated glycolipids in the gas phase. The Journal of Chemical Physics, 2024, 160 (21), ⟨10.1063/5.0211435⟩. ⟨hal-04616644⟩
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- Cécile Labarre, Yijie Zhang, Emilie Lesur, Marie Ley, Laila Sago, et al.. Bioorthogonal Monomycolate of Trehalose Disclosed the O -Mycoloylation of Mycoloyltransferases and Other Cell Envelope Proteins in C. glutamicum. ACS Chemical Biology, 2024, 19 (11), pp.2359-2371. ⟨10.1021/acschembio.4c00502⟩. ⟨hal-04917513⟩
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2023
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- Alexandra Bristiel, Manon Cadinot, Mathieu Pizzonero, Frédéric Taran, Dominique Urban, et al.. 2′-Modified thymidines with bioorthogonal cyclopropene or sydnone as building blocks for copper-free postsynthetic functionalization of chemically synthesized oligonucleotides. Bioconjugate Chemistry, 2023, 34 (9), pp.1613-1621. ⟨10.1021/acs.bioconjchem.3c00284⟩. ⟨hal-04281606⟩
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- D. Liu, O. Monfret, Y. Bourdreux, D. Urban, D. Guianvarc’h, et al.. Fast Access to 5-Hydroxymethyl Derivatives of 2′-Deoxyuridine Promoted by Acidic Amberlyst 15 Resin. SYNLETT, 2023, 34 (02), pp.137-142. ⟨10.1055/a-1961-7251⟩. ⟨hal-04047031⟩
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- Océane Monfret, Dan Liu, Paulin Rollando, Yann Bourdreux, Dominique Urban, et al.. Preparation of 5‐Hydroxymethyl‐pyrimidine Based Nucleosides: A Reinvestigation. European Journal of Organic Chemistry, 2023, 26 (28), ⟨10.1002/ejoc.202300298⟩. ⟨hal-04281656⟩
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2022
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- Mathieu Carlier, Emilie Lesur, Aurélie Baron, Aurélie Lemétais, Karine Guitot, et al.. Synthesis of chemical tools to label the mycomembrane of corynebacteria using modified iron( iii ) chloride-mediated protection of trehalose. Organic & Biomolecular Chemistry, 2022, 20 (9), pp.1974-1981. ⟨10.1039/D2OB00107A⟩. ⟨hal-03801948⟩
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- Blaise Gatin-Fraudet, Mathilde Pucher, Thomas Le Saux, Gilles Doisneau, Yann Bourdreux, et al.. Hydrogen peroxide-responsive triggers based on borinic acids: molecular insights into the control of oxidative rearrangement. Chemistry – A European Journal, In press, 28 (59), pp.e202201543. ⟨10.1002/chem.202201543⟩. ⟨hal-03752143⟩
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2021
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- Blaise Gatin-Fraudet, Roxane Ottenwelter, Thomas Le Saux, Stéphanie Norsikian, Mathilde Pucher, et al.. Evaluation of borinic acids as new, fast hydrogen peroxide–responsive triggers. Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (50), pp.e2107503118. ⟨10.1073/pnas.2107503118⟩. ⟨hal-03542546⟩
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2019
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- Emilie Lesur, Aurélie Baron, Christiane Dietrich, Marie Buchotte, Gilles Doisneau, et al.. First access to a mycolic acid-based bioorthogonal reporter for the study of the mycomembrane and mycoloyltransferases in Corynebacteria. Chemical Communications, 2019, 55 (87), pp.13074-13077. ⟨10.1039/C9CC05754D⟩. ⟨hal-04388218⟩
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2018
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- Jean-Marie Beau, Francois-Didier Boyer, Stéphanie Norsikian, Dominique Urban, Boris Vauzeilles, et al.. Glycosylation: The Direct Synthesis of 2-Acetamido-2-Deoxy-Sugar Glycosides. European Journal of Organic Chemistry, 2018, 2018 (42), pp.5795-5814. ⟨10.1002/ejoc.201800735⟩. ⟨hal-02324798⟩
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2017
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- Nathan Berthelot, Antoine Brossay, Virginie Gasciolli, Jean-Jacques Bono, Aurélie Baron, et al.. Synthesis of lipo-chitooligosaccharide analogues and their interaction with LYR3, a high affinity binding protein for Nod factors and Myc-LCOs. Organic & Biomolecular Chemistry, 2017, 15 (37), pp.7802-7812. ⟨10.1039/c7ob01201b⟩. ⟨hal-02626296⟩
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- Estefania Rossich Molina, Ane Eizaguirre, Violette Haldys, Dominique Urban, Gilles Doisneau, et al.. Characterization of Protonated Model Disaccharides from Tandem Mass Spectrometry and Chemical Dynamics Simulations. ChemPhysChem, 2017, 18 (19), pp.2812 – 2823. ⟨10.1002/cphc.201700202⟩. ⟨hal-01626382⟩
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2015
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- R. Chambon, G. Despras, A. Brossay, B. Vauzeilles, D. Urban, et al.. Efficient chemoenzymatic synthesis of lipo-chitin oligosaccharides as plant growth promoters. Green Chemistry, 2015, 17 (7), pp.3923-3930. ⟨10.1039/C5GC00623F⟩. ⟨hal-01178956⟩
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2014
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- Guillaume Despras, Aurélien Alix, Dominique Urban, Boris Vauzeilles, Jean-Marie Beau. From Chitin to Bioactive Chitooligosaccharides and Conjugates: Access to Lipochitooligosaccharides and the TMG-chitotriomycin.. Angewandte Chemie International Edition, 2014, 53 (44), pp.11912-11916. ⟨10.1002/anie.201406802⟩. ⟨hal-01076451⟩
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- Guillaume Despras, Dominique Urban, Boris Vauzeilles, Jean-Marie Beau. One-pot synthesis of d-glucosamine and chitobiosyl building blocks catalyzed by triflic acid on molecular sieves.. Chemical Communications, 2014, 50 (9), pp.1067-1069. ⟨10.1039/c3cc48078j⟩. ⟨hal-00935849⟩
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- Justine Pezzotta, Dominique Urban, Régis Guillot, Gilles Doisneau, Jean-Marie Beau. Synthesis of spirolactonic C-sialosides induced by samarium diiodide. SYNLETT, 2014, 25 (3), pp.375-380. ⟨10.1055/s-0033-1340067⟩. ⟨hal-00958824⟩
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2013
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- Angie Attouche, Dominique Urban, Jean-Marie Beau. A tin-free regioselective radical de-O-benzylation by an intramolecular hydrogen atom transfer on carbohydrate templates.. Angewandte Chemie International Edition, 2013, 52 (36), pp.9572-5. ⟨10.1002/anie.201301783⟩. ⟨hal-00913390⟩
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Book sections
2019
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- Jean-Marie Beau, Yann Bourdreux, Guillaume Despras, Alexandra Gouasmat, Géraldine San Jose, et al.. One-pot multi-step regioselective protection of carbohydrates catalyzed by acids. Sébastien Vidal. Protecting Groups: Strategies and Applications, 1, Wiley, 2019, ⟨10.1002/9783527697014.ch7⟩. ⟨hal-04519006⟩
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2014
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- J.M. Beau, Yann Bourdreux, F.-D. Boyer, S. Norsikian, D. Urban, et al.. Recent results in synthetic glycochemistry with iron salts at Orsay-Gif. Carbohydrate Chemistry, 40, RSC, pp.118-139, 2014, Volume 40, Chapitre 7, 978-1-84973-965-8. ⟨10.1039/9781849739986-00118⟩. ⟨hal-00972058⟩
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Poster communications
2025
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- Mathilde Pucher, Léa Madegard, Kirrthana Makenthirathasan, Hadrien Jalaber, Thomas Le Saux, et al.. Real-time monitoring oh H2O2 in live cells with novel borinic acid-based fluorogenic probes as an alternative to the Amplex Red assay. Noxros2025: Stress oxydant & régulation rédox dans le Vivant, Nov 2025, Marrakech, Morocco. ⟨hal-05462211⟩
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- Dominique Urban, Léa Madegard, Marie Erard, Oliver Nüsse, Dominique Guianvarc’h. Applying the HALO-Tag strategy to specifically target new borinic acids as hydrogen peroxide-responsive probes to proteins. ChemBioParis2025, Oct 2025, Sorbonne Université (Paris), France. ⟨hal-05395345⟩
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- Dominique Urban, Marie Erard, Oliver Nüsse, Léa Madegard, Dominique Guianvarc’h. Targeting proteins with novel hydrogen peroxide-responsive borinic acid probes using HALO-Tag strategy. Journées de Chimie Organique – (JCO2025), Oct 2025, Palaiseau (91), France. ⟨hal-05394585⟩
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2024
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- Léa Madegard, Marie Erard, Oliver Nüsse, Dominique Guianvarc’h, Dominique Urban. Borinic acids as hydrogen peroxide-responsive probes. RECOB19, Mar 2024, Aussois (France), France. ⟨hal-05395398⟩
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- Léa Madegard, Marie Erard, Oliver Nüsse, Dominique Guianvarc’h, Dominique Urban. Specific targeting of new borinic acids as hydrogen peroxide-responsive probes to proteins using HALO-Tag strategy. PhysChemCell, Oct 2024, Université Paris-Saclay, Orsay, France. ⟨hal-05395370⟩
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Preprints, Working Papers, …
2020
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- Blaise Gatin-Fraudet, Roxane Ottenwelter, Thomas Le Saux, Thomas Lombès, Aurélie Baron, et al.. Borinic acids as new fast-responsive triggers for hydrogen peroxide detection. 2020. ⟨hal-03016626⟩
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